What is CELDA?
The need for detailed description and modeling of cells drives the continuous production of large and diverse datasets, which is confronted with a lack of accessible, systematic and comprehensive organization of these data around cell types.
The CELDA – Ontology (Cell: Expression, Localization, Development, Anatomy) is a structured vocabulary to organize cell-associated data and to place these data in clearly defined semantic relations to otherbiological facts. The CellFinder Ontology describes cell types, their properties and origin and links this information to other existing ontologies like theCell Ontology (CL), Foundational Model of Anatomy (FMA), Gene Ontology (GO), Mouse Anatomy and others using the top-level ontology BioTop.
Furthermore, CELDA is able to describe the development of organs on a cellular level. We started to describe this development for kidney, liver and skin. The CELDA - Ontology is currently used as a data structure to support modeling, analysis and comparison of cells within and across species in the development of the wider research and data repositoryplatform CellFinder.