Gene: CDX2

  • Entrez Gene ID

  • Symbol

    • CDX2
  • Synonyms

    • CDX-3, CDX3
  • Description

    • caudal type homeobox 2
  • Type of Gene

    • protein-coding
  • Chromosome

    • 13
  • Location

    • 13q12.3
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0
    colon
    3.8
    heart
    0
    hypothalamus
    0
    kidney
    0
    liver
    0
    lung
    0
    ovary
    0
    skeletalmuscle
    0
    spleen
    0
    testes
    0
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Negative Supportive
    appendix glandular cells Strong Supportive
    appendix lymphoid tissue Negative Supportive
    bone marrow hematopoietic cells Negative Supportive
    breast glandular cells Negative Supportive
    bronchus respiratory epithelial cells Negative Supportive
    cerebellum cells in granular layer Negative Supportive
    cerebellum cells in molecular layer Negative Supportive
    cerebellum Purkinje cells Negative Supportive
    cerebral cortex glial cells Negative Supportive
    cerebral cortex neuronal cells Negative Supportive
    cervix, uterine glandular cells Negative Supportive
    cervix, uterine squamous epithelial cells Negative Supportive
    colon glandular cells Strong Supportive
    duodenum glandular cells Strong Supportive
    epididymis glandular cells Negative Supportive
    esophagus squamous epithelial cells Negative Supportive
    fallopian tube glandular cells Negative Supportive
    gall bladder glandular cells Negative Supportive
    heart muscle myocytes Negative Supportive
    hippocampus glial cells Negative Supportive
    hippocampus neuronal cells Negative Supportive
    kidney cells in glomeruli Negative Supportive
    kidney cells in tubules Negative Supportive
    lateral ventricle glial cells Negative Supportive
    lateral ventricle neuronal cells Negative Supportive
    liver bile duct cells Negative Supportive
    liver hepatocytes Negative Supportive
    lung macrophages Negative Supportive
    lung pneumocytes Negative Supportive
    lymph node germinal center cells Negative Supportive
    lymph node non-germinal center cells Negative Supportive
    nasopharynx respiratory epithelial cells Negative Supportive
    oral mucosa squamous epithelial cells Negative Supportive
    ovary follicle cells Negative Supportive
    ovary ovarian stroma cells Negative Supportive
    pancreas exocrine glandular cells Negative Supportive
    pancreas islets of Langerhans Negative Supportive
    parathyroid gland glandular cells Negative Supportive
    placenta decidual cells Negative Supportive
    placenta trophoblastic cells Negative Supportive
    prostate glandular cells Negative Supportive
    rectum glandular cells Strong Supportive
    salivary gland glandular cells Negative Supportive
    seminal vesicle glandular cells Negative Supportive
    skeletal muscle myocytes Negative Supportive
    skin epidermal cells Negative Supportive
    small intestine glandular cells Moderate Supportive
    smooth muscle smooth muscle cells Negative Supportive
    spleen cells in red pulp Negative Supportive
    spleen cells in white pulp Negative Supportive
    stomach, lower glandular cells Negative Supportive
    stomach, upper glandular cells Negative Supportive
    testis cells in seminiferus ducts Negative Supportive
    testis Leydig cells Negative Supportive
    thyroid gland glandular cells Negative Supportive
    tonsil germinal center cells Negative Supportive
    tonsil non-germinal center cells Negative Supportive
    urinary bladder urothelial cells Negative Supportive
    uterus, post-menopause cells in endometrial stroma Negative Supportive
    uterus, post-menopause glandular cells Negative Supportive
    uterus, pre-menopause cells in endometrial stroma Negative Supportive
    uterus, pre-menopause glandular cells Negative Supportive
    vagina squamous epithelial cells Negative Supportive
    vulva/anal skin epidermal cells Negative Supportive
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0000794 condensed nuclear chromosome Component
    GO:0017053 transcriptional repressor complex Component
    GO:0003700 sequence-specific DNA binding transcription factor activity Function
    GO:0003714 transcription corepressor activity Function
    GO:0000976 transcription regulatory region sequence-specific DNA binding Function
    GO:0009952 anterior/posterior pattern specification Process
    GO:0001568 blood vessel development Process
    GO:0008333 endosome to lysosome transport Process
    GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity Process
    GO:0060711 labyrinthine layer development Process
    GO:0000122 negative regulation of transcription from RNA polymerase II promoter Process
    GO:0009887 organ morphogenesis 9052785 Process
    GO:0045597 positive regulation of cell differentiation Process
    GO:0035019 somatic stem cell maintenance Process
    GO:0006366 transcription from RNA polymerase II promoter 9459001 Process
    GO:0001829 trophectodermal cell differentiation Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084