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Entrez Gene ID
- 1280 (Go to NCBI)
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Symbol
- COL2A1
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Synonyms
- ANFH, AOM, COL11A3, SEDC
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Description
- collagen, type II, alpha 1
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Type of Gene
- protein-coding
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Chromosome
- 12
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Location
- 12q13.11
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RNA Seq 1
Sample Expression RPKM adipose 0 colon 0.02 heart 0 hypothalamus 0.06 kidney 0 liver 0 lung 0.02 ovary 0.11 skeletalmuscle 0 spleen 0 testes 0.02 -
Protein
Tissue Cell type Staining level Reliability adrenal gland glandular cells Negative Uncertain appendix glandular cells Weak Uncertain appendix lymphoid tissue Negative Uncertain bone marrow hematopoietic cells Negative Uncertain breast glandular cells Negative Uncertain bronchus respiratory epithelial cells Negative Uncertain cerebellum cells in granular layer Negative Uncertain cerebellum cells in molecular layer Negative Uncertain cerebellum Purkinje cells Negative Uncertain cerebral cortex glial cells Negative Uncertain cerebral cortex neuronal cells Negative Uncertain cervix, uterine glandular cells Negative Uncertain cervix, uterine squamous epithelial cells Negative Uncertain colon glandular cells Weak Uncertain duodenum glandular cells Weak Uncertain epididymis glandular cells Negative Uncertain esophagus squamous epithelial cells Negative Uncertain fallopian tube glandular cells Negative Uncertain gall bladder glandular cells Negative Uncertain heart muscle myocytes Negative Uncertain hippocampus glial cells Negative Uncertain hippocampus neuronal cells Negative Uncertain kidney cells in glomeruli Negative Uncertain kidney cells in tubules Negative Uncertain lateral ventricle glial cells Negative Uncertain lateral ventricle neuronal cells Negative Uncertain liver bile duct cells Negative Uncertain liver hepatocytes Weak Uncertain lung macrophages Negative Uncertain lung pneumocytes Negative Uncertain lymph node germinal center cells Negative Uncertain lymph node non-germinal center cells Negative Uncertain nasopharynx respiratory epithelial cells Negative Uncertain oral mucosa squamous epithelial cells Negative Uncertain ovary follicle cells Negative Uncertain ovary ovarian stroma cells Negative Uncertain pancreas exocrine glandular cells Negative Uncertain pancreas islets of Langerhans Negative Uncertain parathyroid gland glandular cells Negative Uncertain placenta trophoblastic cells Negative Uncertain prostate glandular cells Negative Uncertain rectum glandular cells Weak Uncertain salivary gland glandular cells Negative Uncertain seminal vesicle glandular cells Negative Uncertain skeletal muscle myocytes Negative Uncertain skin epidermal cells Weak Uncertain small intestine glandular cells Weak Uncertain smooth muscle smooth muscle cells Negative Uncertain spleen cells in red pulp Negative Uncertain spleen cells in white pulp Negative Uncertain stomach, lower glandular cells Weak Uncertain stomach, upper glandular cells Negative Uncertain testis cells in seminiferus ducts Negative Uncertain testis Leydig cells Negative Uncertain thyroid gland glandular cells Negative Uncertain tonsil germinal center cells Negative Uncertain tonsil non-germinal center cells Negative Uncertain tonsil squamous epithelial cells Negative Uncertain urinary bladder urothelial cells Weak Uncertain uterus, post-menopause cells in endometrial stroma Negative Uncertain uterus, post-menopause glandular cells Negative Uncertain uterus, pre-menopause cells in endometrial stroma Negative Uncertain uterus, pre-menopause glandular cells Negative Uncertain vagina squamous epithelial cells Negative Uncertain vulva/anal skin epidermal cells Weak Uncertain -
Gene Ontology
GO ID GO term PubMed Category GO:0005604 basement membrane Component GO:0005585 collagen type II 8660302 Component GO:0005788 endoplasmic reticulum lumen Component GO:0005576 extracellular region Component GO:0005615 extracellular space Component GO:0030020 extracellular matrix structural constituent conferring tensile strength 8660302 Function GO:0042802 identical protein binding 2587267 Function GO:0048407 platelet-derived growth factor binding 8900172 Function GO:0007411 axon guidance Process GO:0001502 cartilage condensation Process GO:0051216 cartilage development 7550321 Process GO:0060351 cartilage development involved in endochondral bone morphogenesis Process GO:0071773 cellular response to BMP stimulus Process GO:0007417 central nervous system development Process GO:0002062 chondrocyte differentiation Process GO:0030199 collagen fibril organization 1429602 Process GO:0060272 embryonic skeletal joint morphogenesis 16752401 Process GO:0001958 endochondral ossification Process GO:0030198 extracellular matrix organization Process GO:0003007 heart morphogenesis Process GO:0042472 inner ear morphogenesis Process GO:0060174 limb bud formation Process GO:0043066 negative regulation of apoptotic process Process GO:0030903 notochord development Process GO:0071599 otic vesicle development Process GO:0060021 palate development Process GO:0006029 proteoglycan metabolic process Process GO:0010468 regulation of gene expression Process GO:0007605 sensory perception of sound 16752401 Process GO:0001501 skeletal system development 1429602 Process GO:0001894 tissue homeostasis Process GO:0007601 visual perception 10486316 Process
- Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084