Gene: COL2A1

  • Entrez Gene ID

  • Symbol

    • COL2A1

  • Synonyms

    • ANFH, AOM, COL11A3, SEDC

  • Description

    • collagen, type II, alpha 1

  • Type of Gene

    • protein-coding

  • Chromosome

    • 12

  • Location

    • 12q13.11

  • RNA Seq 1

    Sample Expression RPKM
    adipose
    		0
    colon
    		0.02
    heart
    		0
    hypothalamus
    		0.06
    kidney
    		0
    liver
    		0
    lung
    		0.02
    ovary
    		0.11
    skeletalmuscle
    		0
    spleen
    		0
    testes
    		0.02

  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Negative Uncertain
    appendix glandular cells Weak Uncertain
    appendix lymphoid tissue Negative Uncertain
    bone marrow hematopoietic cells Negative Uncertain
    breast glandular cells Negative Uncertain
    bronchus respiratory epithelial cells Negative Uncertain
    cerebellum cells in granular layer Negative Uncertain
    cerebellum cells in molecular layer Negative Uncertain
    cerebellum Purkinje cells Negative Uncertain
    cerebral cortex glial cells Negative Uncertain
    cerebral cortex neuronal cells Negative Uncertain
    cervix, uterine glandular cells Negative Uncertain
    cervix, uterine squamous epithelial cells Negative Uncertain
    colon glandular cells Weak Uncertain
    duodenum glandular cells Weak Uncertain
    epididymis glandular cells Negative Uncertain
    esophagus squamous epithelial cells Negative Uncertain
    fallopian tube glandular cells Negative Uncertain
    gall bladder glandular cells Negative Uncertain
    heart muscle myocytes Negative Uncertain
    hippocampus glial cells Negative Uncertain
    hippocampus neuronal cells Negative Uncertain
    kidney cells in glomeruli Negative Uncertain
    kidney cells in tubules Negative Uncertain
    lateral ventricle glial cells Negative Uncertain
    lateral ventricle neuronal cells Negative Uncertain
    liver bile duct cells Negative Uncertain
    liver hepatocytes Weak Uncertain
    lung macrophages Negative Uncertain
    lung pneumocytes Negative Uncertain
    lymph node germinal center cells Negative Uncertain
    lymph node non-germinal center cells Negative Uncertain
    nasopharynx respiratory epithelial cells Negative Uncertain
    oral mucosa squamous epithelial cells Negative Uncertain
    ovary follicle cells Negative Uncertain
    ovary ovarian stroma cells Negative Uncertain
    pancreas exocrine glandular cells Negative Uncertain
    pancreas islets of Langerhans Negative Uncertain
    parathyroid gland glandular cells Negative Uncertain
    placenta trophoblastic cells Negative Uncertain
    prostate glandular cells Negative Uncertain
    rectum glandular cells Weak Uncertain
    salivary gland glandular cells Negative Uncertain
    seminal vesicle glandular cells Negative Uncertain
    skeletal muscle myocytes Negative Uncertain
    skin epidermal cells Weak Uncertain
    small intestine glandular cells Weak Uncertain
    smooth muscle smooth muscle cells Negative Uncertain
    spleen cells in red pulp Negative Uncertain
    spleen cells in white pulp Negative Uncertain
    stomach, lower glandular cells Weak Uncertain
    stomach, upper glandular cells Negative Uncertain
    testis cells in seminiferus ducts Negative Uncertain
    testis Leydig cells Negative Uncertain
    thyroid gland glandular cells Negative Uncertain
    tonsil germinal center cells Negative Uncertain
    tonsil non-germinal center cells Negative Uncertain
    tonsil squamous epithelial cells Negative Uncertain
    urinary bladder urothelial cells Weak Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Negative Uncertain
    uterus, pre-menopause cells in endometrial stroma Negative Uncertain
    uterus, pre-menopause glandular cells Negative Uncertain
    vagina squamous epithelial cells Negative Uncertain
    vulva/anal skin epidermal cells Weak Uncertain

  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005604 basement membrane Component
    GO:0005585 collagen type II 8660302 Component
    GO:0005788 endoplasmic reticulum lumen Component
    GO:0005576 extracellular region Component
    GO:0005615 extracellular space Component
    GO:0030020 extracellular matrix structural constituent conferring tensile strength 8660302 Function
    GO:0042802 identical protein binding 2587267 Function
    GO:0048407 platelet-derived growth factor binding 8900172 Function
    GO:0007411 axon guidance Process
    GO:0001502 cartilage condensation Process
    GO:0051216 cartilage development 7550321 Process
    GO:0060351 cartilage development involved in endochondral bone morphogenesis Process
    GO:0071773 cellular response to BMP stimulus Process
    GO:0007417 central nervous system development Process
    GO:0002062 chondrocyte differentiation Process
    GO:0030199 collagen fibril organization 1429602 Process
    GO:0060272 embryonic skeletal joint morphogenesis 16752401 Process
    GO:0001958 endochondral ossification Process
    GO:0030198 extracellular matrix organization Process
    GO:0003007 heart morphogenesis Process
    GO:0042472 inner ear morphogenesis Process
    GO:0060174 limb bud formation Process
    GO:0043066 negative regulation of apoptotic process Process
    GO:0030903 notochord development Process
    GO:0071599 otic vesicle development Process
    GO:0060021 palate development Process
    GO:0006029 proteoglycan metabolic process Process
    GO:0010468 regulation of gene expression Process
    GO:0007605 sensory perception of sound 16752401 Process
    GO:0001501 skeletal system development 1429602 Process
    GO:0001894 tissue homeostasis Process
    GO:0007601 visual perception 10486316 Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084