Gene: CTNNA1

  • Entrez Gene ID

  • Symbol

    • CTNNA1
  • Synonyms

    • CAP102
  • Description

    • catenin (cadherin-associated protein), alpha 1, 102kDa
  • Type of Gene

    • protein-coding
  • Chromosome

    • 5
  • Location

    • 5q31.2
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    24.24
    colon
    15.92
    heart
    43.54
    hypothalamus
    19.64
    kidney
    37.68
    liver
    17.9
    lung
    32.12
    ovary
    20.91
    skeletalmuscle
    11.97
    spleen
    26.94
    testes
    18.5
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Moderate Supportive
    appendix glandular cells Strong Supportive
    appendix lymphoid tissue Weak Supportive
    bone marrow hematopoietic cells Moderate Supportive
    breast glandular cells Moderate Supportive
    bronchus respiratory epithelial cells Strong Supportive
    cerebellum cells in granular layer Weak Supportive
    cerebellum cells in molecular layer Weak Supportive
    cerebellum Purkinje cells Weak Supportive
    cerebral cortex glial cells Negative Supportive
    cerebral cortex neuronal cells Moderate Supportive
    cervix, uterine squamous epithelial cells Weak Supportive
    colon glandular cells Moderate Supportive
    duodenum glandular cells Strong Supportive
    epididymis glandular cells Strong Supportive
    esophagus squamous epithelial cells Weak Supportive
    fallopian tube glandular cells Strong Supportive
    gall bladder glandular cells Strong Supportive
    heart muscle myocytes Moderate Supportive
    hippocampus glial cells Weak Supportive
    hippocampus neuronal cells Moderate Supportive
    kidney cells in glomeruli Negative Supportive
    kidney cells in tubules Strong Supportive
    lateral ventricle glial cells Weak Supportive
    lateral ventricle neuronal cells Moderate Supportive
    liver bile duct cells Strong Supportive
    liver hepatocytes Strong Supportive
    lung macrophages Moderate Supportive
    lung pneumocytes Strong Supportive
    lymph node germinal center cells Negative Supportive
    lymph node non-germinal center cells Negative Supportive
    nasopharynx respiratory epithelial cells Moderate Supportive
    oral mucosa squamous epithelial cells Negative Supportive
    ovary ovarian stroma cells Negative Supportive
    pancreas exocrine glandular cells Strong Supportive
    parathyroid gland glandular cells Weak Supportive
    placenta trophoblastic cells Strong Supportive
    prostate glandular cells Strong Supportive
    rectum glandular cells Moderate Supportive
    salivary gland glandular cells Moderate Supportive
    seminal vesicle glandular cells Strong Supportive
    skeletal muscle myocytes Negative Supportive
    skin epidermal cells Moderate Supportive
    small intestine glandular cells Strong Supportive
    smooth muscle smooth muscle cells Negative Supportive
    spleen cells in red pulp Weak Supportive
    spleen cells in white pulp Weak Supportive
    stomach, lower glandular cells Strong Supportive
    stomach, upper glandular cells Strong Supportive
    testis cells in seminiferus ducts Moderate Supportive
    testis Leydig cells Strong Supportive
    thyroid gland glandular cells Moderate Supportive
    tonsil germinal center cells Weak Supportive
    tonsil non-germinal center cells Weak Supportive
    tonsil squamous epithelial cells Negative Supportive
    urinary bladder urothelial cells Moderate Supportive
    uterus, post-menopause cells in endometrial stroma Negative Supportive
    uterus, post-menopause glandular cells Strong Supportive
    uterus, pre-menopause cells in endometrial stroma Negative Supportive
    uterus, pre-menopause glandular cells Moderate Supportive
    vagina squamous epithelial cells Negative Supportive
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0001669 acrosomal vesicle Component
    GO:0015629 actin cytoskeleton Component
    GO:0016342 catenin complex 7650039 Component
    GO:0005911 cell-cell junction 10460003 Component
    GO:0005829 cytosol Component
    GO:0030027 lamellipodium Component
    GO:0005886 plasma membrane Component
    GO:0005915 zonula adherens Component
    GO:0051015 actin filament binding Function
    GO:0008013 beta-catenin binding 7650039 Function
    GO:0045296 cadherin binding 12734196 Function
    GO:0045295 gamma-catenin binding 7650039 Function
    GO:0005515 protein binding 12477722 Function
    GO:0005198 structural molecule activity Function
    GO:0017166 vinculin binding 9700171 Function
    GO:0034332 adherens junction organization Process
    GO:0007568 aging Process
    GO:0043297 apical junction assembly 9700171 Process
    GO:0031103 axon regeneration Process
    GO:0007155 cell adhesion Process
    GO:0034329 cell junction assembly Process
    GO:0045216 cell-cell junction organization Process
    GO:0071681 cellular response to indole-3-methanol 10868478 Process
    GO:0007163 establishment or maintenance of cell polarity Process
    GO:0016264 gap junction assembly Process
    GO:0008584 male gonad development Process
    GO:0042692 muscle cell differentiation Process
    GO:0043066 negative regulation of apoptotic process Process
    GO:0007406 negative regulation of neuroblast proliferation Process
    GO:0042475 odontogenesis of dentin-containing tooth Process
    GO:0001541 ovarian follicle development Process
    GO:0051149 positive regulation of muscle cell differentiation Process
    GO:0045880 positive regulation of smoothened signaling pathway Process
    GO:0043627 response to estrogen stimulus Process
    GO:0014070 response to organic cyclic compound Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084