Gene: DUSP4

  • Entrez Gene ID

  • Symbol

    • DUSP4
  • Synonyms

    • HVH2, MKP-2, MKP2, TYP
  • Description

    • dual specificity phosphatase 4
  • Type of Gene

    • protein-coding
  • Chromosome

    • 8
  • Location

    • 8p12-p11
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.38
    colon
    0.05
    heart
    0.31
    hypothalamus
    0.28
    kidney
    0.04
    liver
    0.03
    lung
    0.33
    ovary
    0.04
    skeletalmuscle
    0.12
    spleen
    0.06
    testes
    0.08
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005654 nucleoplasm Component
    GO:0005634 nucleus 7535768 Component
    GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity Function
    GO:0004725 protein tyrosine phosphatase activity Function
    GO:0008330 protein tyrosine/threonine phosphatase activity Function
    GO:0001706 endoderm formation Process
    GO:0000188 inactivation of MAPK activity Process
    GO:0045087 innate immune response Process
    GO:0000165 MAPK cascade 7535768 Process
    GO:0002755 MyD88-dependent toll-like receptor signaling pathway Process
    GO:0002756 MyD88-independent toll-like receptor signaling pathway Process
    GO:0048011 nerve growth factor receptor signaling pathway Process
    GO:0006470 protein dephosphorylation Process
    GO:0010033 response to organic substance Process
    GO:0051403 stress-activated MAPK cascade Process
    GO:0008063 Toll signaling pathway Process
    GO:0034130 toll-like receptor 1 signaling pathway Process
    GO:0034134 toll-like receptor 2 signaling pathway Process
    GO:0034138 toll-like receptor 3 signaling pathway Process
    GO:0034142 toll-like receptor 4 signaling pathway Process
    GO:0002224 toll-like receptor signaling pathway Process
    GO:0035666 TRIF-dependent toll-like receptor signaling pathway Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084