Gene: EDNRB

  • Entrez Gene ID

  • Symbol

    • EDNRB

  • Synonyms

    • ABCDS, ET-B, ET-BR, ETB, ETBR, ETRB, HSCR, HSCR2, WS4A

  • Description

    • endothelin receptor type B

  • Type of Gene

    • protein-coding

  • Chromosome

    • 13

  • Location

    • 13q22

  • RNA Seq 1

    Sample Expression RPKM
    adipose
    		3.81
    colon
    		0.97
    heart
    		6.72
    hypothalamus
    		7.64
    kidney
    		6.01
    liver
    		5.14
    lung
    		8.6
    ovary
    		0.71
    skeletalmuscle
    		0.73
    spleen
    		10.24
    testes
    		1.48

  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Strong Uncertain
    appendix glandular cells Moderate Uncertain
    bone marrow hematopoietic cells Strong Uncertain
    breast glandular cells Strong Uncertain
    bronchus respiratory epithelial cells Strong Uncertain
    cerebellum cells in granular layer Weak Uncertain
    cerebellum cells in molecular layer Moderate Uncertain
    cerebellum Purkinje cells Weak Uncertain
    cerebral cortex glial cells Moderate Uncertain
    cerebral cortex neuronal cells Moderate Uncertain
    cervix, uterine glandular cells Negative Uncertain
    cervix, uterine squamous epithelial cells Weak Uncertain
    colon glandular cells Strong Uncertain
    duodenum glandular cells Strong Uncertain
    epididymis glandular cells Moderate Uncertain
    esophagus squamous epithelial cells Moderate Uncertain
    fallopian tube glandular cells Strong Uncertain
    gall bladder glandular cells Strong Uncertain
    heart muscle myocytes Moderate Uncertain
    hippocampus glial cells Weak Uncertain
    hippocampus neuronal cells Weak Uncertain
    kidney cells in glomeruli Moderate Uncertain
    kidney cells in tubules Strong Uncertain
    lateral ventricle glial cells Weak Uncertain
    lateral ventricle neuronal cells Moderate Uncertain
    liver bile duct cells Moderate Uncertain
    liver hepatocytes Moderate Uncertain
    lung macrophages Moderate Uncertain
    lung pneumocytes Weak Uncertain
    lymph node germinal center cells Weak Uncertain
    lymph node non-germinal center cells Moderate Uncertain
    nasopharynx respiratory epithelial cells Strong Uncertain
    oral mucosa squamous epithelial cells Strong Uncertain
    ovary follicle cells Moderate Uncertain
    ovary ovarian stroma cells Moderate Uncertain
    pancreas exocrine glandular cells Negative Uncertain
    pancreas islets of Langerhans Negative Uncertain
    parathyroid gland glandular cells Strong Uncertain
    placenta decidual cells Moderate Uncertain
    placenta trophoblastic cells Moderate Uncertain
    prostate glandular cells Negative Uncertain
    rectum glandular cells Strong Uncertain
    salivary gland glandular cells Moderate Uncertain
    seminal vesicle glandular cells Moderate Uncertain
    skeletal muscle myocytes Strong Uncertain
    skin epidermal cells Weak Uncertain
    small intestine glandular cells Strong Uncertain
    smooth muscle smooth muscle cells Moderate Uncertain
    spleen cells in red pulp Moderate Uncertain
    spleen cells in white pulp Negative Uncertain
    stomach, lower glandular cells Moderate Uncertain
    stomach, upper glandular cells Moderate Uncertain
    testis cells in seminiferus ducts Strong Uncertain
    testis Leydig cells Strong Uncertain
    thyroid gland glandular cells Moderate Uncertain
    tonsil germinal center cells Strong Uncertain
    tonsil non-germinal center cells Moderate Uncertain
    tonsil squamous epithelial cells Moderate Uncertain
    urinary bladder urothelial cells Strong Uncertain
    uterus, post-menopause cells in endometrial stroma Moderate Uncertain
    uterus, post-menopause glandular cells Strong Uncertain
    uterus, pre-menopause cells in endometrial stroma Weak Uncertain
    uterus, pre-menopause glandular cells Moderate Uncertain
    vagina squamous epithelial cells Weak Uncertain
    vulva/anal skin epidermal cells Weak Uncertain

  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005887 integral to plasma membrane 8810293 Component
    GO:0005886 plasma membrane Component
    GO:0004962 endothelin receptor activity 1713452 Function
    GO:0004962 endothelin receptor activity 19767294 Function
    GO:0017046 peptide hormone binding 1713452 Function
    GO:0007166 cell surface receptor signaling pathway 8810293 Process
    GO:0086100 endothelin receptor signaling pathway 1713452 Process
    GO:0086100 endothelin receptor signaling pathway 19767294 Process
    GO:0048484 enteric nervous system development Process
    GO:0035645 enteric smooth muscle cell differentiation Process
    GO:0048246 macrophage chemotaxis 12207323 Process
    GO:0030318 melanocyte differentiation Process
    GO:0007194 negative regulation of adenylate cyclase activity 9556633 Process
    GO:0032269 negative regulation of cellular protein metabolic process 19767294 Process
    GO:0014043 negative regulation of neuron maturation Process
    GO:0000122 negative regulation of transcription from RNA polymerase II promoter 19767294 Process
    GO:0000122 negative regulation of transcription from RNA polymerase II promoter Process
    GO:0007399 nervous system development 8001158 Process
    GO:0001755 neural crest cell migration Process
    GO:0007422 peripheral nervous system development Process
    GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway 9556633 Process
    GO:0007497 posterior midgut development Process
    GO:0008217 regulation of blood pressure Process
    GO:0006885 regulation of pH Process
    GO:0042310 vasoconstriction 8982507 Process
    GO:0014826 vein smooth muscle contraction 8982507 Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084