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Entrez Gene ID
- 1910 (Go to NCBI)
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Symbol
- EDNRB
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Synonyms
- ABCDS, ET-B, ET-BR, ETB, ETBR, ETRB, HSCR, HSCR2, WS4A
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Description
- endothelin receptor type B
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Type of Gene
- protein-coding
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Chromosome
- 13
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Location
- 13q22
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RNA Seq 1
Sample Expression RPKM adipose 3.81 colon 0.97 heart 6.72 hypothalamus 7.64 kidney 6.01 liver 5.14 lung 8.6 ovary 0.71 skeletalmuscle 0.73 spleen 10.24 testes 1.48 -
Protein
Tissue Cell type Staining level Reliability adrenal gland glandular cells Strong Uncertain appendix glandular cells Moderate Uncertain bone marrow hematopoietic cells Strong Uncertain breast glandular cells Strong Uncertain bronchus respiratory epithelial cells Strong Uncertain cerebellum cells in granular layer Weak Uncertain cerebellum cells in molecular layer Moderate Uncertain cerebellum Purkinje cells Weak Uncertain cerebral cortex glial cells Moderate Uncertain cerebral cortex neuronal cells Moderate Uncertain cervix, uterine glandular cells Negative Uncertain cervix, uterine squamous epithelial cells Weak Uncertain colon glandular cells Strong Uncertain duodenum glandular cells Strong Uncertain epididymis glandular cells Moderate Uncertain esophagus squamous epithelial cells Moderate Uncertain fallopian tube glandular cells Strong Uncertain gall bladder glandular cells Strong Uncertain heart muscle myocytes Moderate Uncertain hippocampus glial cells Weak Uncertain hippocampus neuronal cells Weak Uncertain kidney cells in glomeruli Moderate Uncertain kidney cells in tubules Strong Uncertain lateral ventricle glial cells Weak Uncertain lateral ventricle neuronal cells Moderate Uncertain liver bile duct cells Moderate Uncertain liver hepatocytes Moderate Uncertain lung macrophages Moderate Uncertain lung pneumocytes Weak Uncertain lymph node germinal center cells Weak Uncertain lymph node non-germinal center cells Moderate Uncertain nasopharynx respiratory epithelial cells Strong Uncertain oral mucosa squamous epithelial cells Strong Uncertain ovary follicle cells Moderate Uncertain ovary ovarian stroma cells Moderate Uncertain pancreas exocrine glandular cells Negative Uncertain pancreas islets of Langerhans Negative Uncertain parathyroid gland glandular cells Strong Uncertain placenta decidual cells Moderate Uncertain placenta trophoblastic cells Moderate Uncertain prostate glandular cells Negative Uncertain rectum glandular cells Strong Uncertain salivary gland glandular cells Moderate Uncertain seminal vesicle glandular cells Moderate Uncertain skeletal muscle myocytes Strong Uncertain skin epidermal cells Weak Uncertain small intestine glandular cells Strong Uncertain smooth muscle smooth muscle cells Moderate Uncertain spleen cells in red pulp Moderate Uncertain spleen cells in white pulp Negative Uncertain stomach, lower glandular cells Moderate Uncertain stomach, upper glandular cells Moderate Uncertain testis cells in seminiferus ducts Strong Uncertain testis Leydig cells Strong Uncertain thyroid gland glandular cells Moderate Uncertain tonsil germinal center cells Strong Uncertain tonsil non-germinal center cells Moderate Uncertain tonsil squamous epithelial cells Moderate Uncertain urinary bladder urothelial cells Strong Uncertain uterus, post-menopause cells in endometrial stroma Moderate Uncertain uterus, post-menopause glandular cells Strong Uncertain uterus, pre-menopause cells in endometrial stroma Weak Uncertain uterus, pre-menopause glandular cells Moderate Uncertain vagina squamous epithelial cells Weak Uncertain vulva/anal skin epidermal cells Weak Uncertain -
Gene Ontology
GO ID GO term PubMed Category GO:0005887 integral to plasma membrane 8810293 Component GO:0005886 plasma membrane Component GO:0004962 endothelin receptor activity 1713452 Function GO:0004962 endothelin receptor activity 19767294 Function GO:0017046 peptide hormone binding 1713452 Function GO:0007166 cell surface receptor signaling pathway 8810293 Process GO:0086100 endothelin receptor signaling pathway 1713452 Process GO:0086100 endothelin receptor signaling pathway 19767294 Process GO:0048484 enteric nervous system development Process GO:0035645 enteric smooth muscle cell differentiation Process GO:0048246 macrophage chemotaxis 12207323 Process GO:0030318 melanocyte differentiation Process GO:0007194 negative regulation of adenylate cyclase activity 9556633 Process GO:0032269 negative regulation of cellular protein metabolic process 19767294 Process GO:0014043 negative regulation of neuron maturation Process GO:0000122 negative regulation of transcription from RNA polymerase II promoter 19767294 Process GO:0000122 negative regulation of transcription from RNA polymerase II promoter Process GO:0007399 nervous system development 8001158 Process GO:0001755 neural crest cell migration Process GO:0007422 peripheral nervous system development Process GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway 9556633 Process GO:0007497 posterior midgut development Process GO:0008217 regulation of blood pressure Process GO:0006885 regulation of pH Process GO:0042310 vasoconstriction 8982507 Process GO:0014826 vein smooth muscle contraction 8982507 Process
- Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084