Gene: EN1

  • Entrez Gene ID

  • Symbol

    • EN1
  • Synonyms

  • Description

    • engrailed homeobox 1
  • Type of Gene

    • protein-coding
  • Chromosome

    • 2
  • Location

    • 2q14.2
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.46
    colon
    0.07
    heart
    0.08
    hypothalamus
    0.19
    kidney
    0.08
    liver
    0.47
    lung
    1.37
    ovary
    0.04
    skeletalmuscle
    0.49
    spleen
    0.06
    testes
    0.37
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Strong Supportive
    appendix glandular cells Strong Supportive
    appendix lymphoid tissue Strong Supportive
    bone marrow hematopoietic cells Moderate Supportive
    breast glandular cells Strong Supportive
    bronchus respiratory epithelial cells Strong Supportive
    cerebellum cells in granular layer Strong Supportive
    cerebellum cells in molecular layer Strong Supportive
    cerebellum Purkinje cells Strong Supportive
    cerebral cortex glial cells Strong Supportive
    cerebral cortex neuronal cells Strong Supportive
    cervix, uterine glandular cells Strong Supportive
    cervix, uterine squamous epithelial cells Strong Supportive
    colon glandular cells Strong Supportive
    duodenum glandular cells Strong Supportive
    epididymis glandular cells Strong Supportive
    esophagus squamous epithelial cells Strong Supportive
    fallopian tube glandular cells Strong Supportive
    gall bladder glandular cells Strong Supportive
    heart muscle myocytes Moderate Supportive
    hippocampus glial cells Strong Supportive
    hippocampus neuronal cells Strong Supportive
    kidney cells in glomeruli Strong Supportive
    kidney cells in tubules Strong Supportive
    lateral ventricle glial cells Strong Supportive
    lateral ventricle neuronal cells Strong Supportive
    liver bile duct cells Strong Supportive
    liver hepatocytes Moderate Supportive
    lung macrophages Moderate Supportive
    lung pneumocytes Strong Supportive
    lymph node germinal center cells Strong Supportive
    lymph node non-germinal center cells Strong Supportive
    nasopharynx respiratory epithelial cells Strong Supportive
    oral mucosa squamous epithelial cells Strong Supportive
    ovary follicle cells Strong Supportive
    ovary ovarian stroma cells Strong Supportive
    pancreas exocrine glandular cells Strong Supportive
    pancreas islets of Langerhans Strong Supportive
    parathyroid gland glandular cells Strong Supportive
    placenta decidual cells Strong Supportive
    placenta trophoblastic cells Strong Supportive
    prostate glandular cells Strong Supportive
    rectum glandular cells Strong Supportive
    salivary gland glandular cells Strong Supportive
    seminal vesicle glandular cells Strong Supportive
    skeletal muscle myocytes Strong Supportive
    skin epidermal cells Strong Supportive
    small intestine glandular cells Strong Supportive
    smooth muscle smooth muscle cells Strong Supportive
    spleen cells in red pulp Strong Supportive
    spleen cells in white pulp Strong Supportive
    stomach, lower glandular cells Strong Supportive
    stomach, upper glandular cells Strong Supportive
    testis cells in seminiferus ducts Strong Supportive
    testis Leydig cells Strong Supportive
    thyroid gland glandular cells Strong Supportive
    tonsil germinal center cells Strong Supportive
    tonsil non-germinal center cells Strong Supportive
    tonsil squamous epithelial cells Strong Supportive
    urinary bladder urothelial cells Strong Supportive
    uterus, post-menopause cells in endometrial stroma Strong Supportive
    uterus, post-menopause glandular cells Strong Supportive
    uterus, pre-menopause cells in endometrial stroma Moderate Supportive
    uterus, pre-menopause glandular cells Moderate Supportive
    vagina squamous epithelial cells Strong Supportive
    vulva/anal skin epidermal cells Strong Supportive
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005634 nucleus Component
    GO:0043565 sequence-specific DNA binding Function
    GO:0003700 sequence-specific DNA binding transcription factor activity Function
    GO:0009653 anatomical structure morphogenesis 8094370 Process
    GO:0009953 dorsal/ventral pattern formation Process
    GO:0035115 embryonic forelimb morphogenesis Process
    GO:0030902 hindbrain development Process
    GO:0030901 midbrain development Process
    GO:0030917 midbrain-hindbrain boundary development Process
    GO:0048666 neuron development Process
    GO:0043473 pigmentation Process
    GO:0045944 positive regulation of transcription from RNA polymerase II promoter Process
    GO:0009954 proximal/distal pattern formation Process
    GO:0001501 skeletal system development 8684466 Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084