Gene: EPHA1

  • Entrez Gene ID

  • Symbol

    • EPHA1
  • Synonyms

    • EPH, EPHT, EPHT1
  • Description

    • EPH receptor A1
  • Type of Gene

    • protein-coding
  • Chromosome

    • 7
  • Location

    • 7q34
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.05
    colon
    0.69
    heart
    0.02
    hypothalamus
    0.03
    kidney
    0.42
    liver
    2.3
    lung
    0.23
    ovary
    0.1
    skeletalmuscle
    0.05
    spleen
    0.15
    testes
    0.16
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Strong Uncertain
    appendix glandular cells Strong Uncertain
    appendix lymphoid tissue Moderate Uncertain
    bone marrow hematopoietic cells Weak Uncertain
    breast glandular cells Moderate Uncertain
    bronchus respiratory epithelial cells Moderate Uncertain
    cerebellum cells in granular layer Weak Uncertain
    cerebellum cells in molecular layer Moderate Uncertain
    cerebellum Purkinje cells Moderate Uncertain
    cerebral cortex glial cells Moderate Uncertain
    cerebral cortex neuronal cells Strong Uncertain
    cervix, uterine glandular cells Moderate Uncertain
    cervix, uterine squamous epithelial cells Moderate Uncertain
    colon glandular cells Moderate Uncertain
    duodenum glandular cells Moderate Uncertain
    epididymis glandular cells Strong Uncertain
    esophagus squamous epithelial cells Moderate Uncertain
    fallopian tube glandular cells Moderate Uncertain
    gall bladder glandular cells Strong Uncertain
    heart muscle myocytes Strong Uncertain
    hippocampus glial cells Moderate Uncertain
    hippocampus neuronal cells Strong Uncertain
    kidney cells in glomeruli Weak Uncertain
    kidney cells in tubules Moderate Uncertain
    lateral ventricle glial cells Moderate Uncertain
    lateral ventricle neuronal cells Strong Uncertain
    liver bile duct cells Moderate Uncertain
    liver hepatocytes Moderate Uncertain
    lung macrophages Strong Uncertain
    lung pneumocytes Moderate Uncertain
    lymph node germinal center cells Moderate Uncertain
    lymph node non-germinal center cells Moderate Uncertain
    nasopharynx respiratory epithelial cells Moderate Uncertain
    oral mucosa squamous epithelial cells Moderate Uncertain
    ovary ovarian stroma cells Weak Uncertain
    pancreas exocrine glandular cells Strong Uncertain
    pancreas islets of Langerhans Strong Uncertain
    parathyroid gland glandular cells Strong Uncertain
    placenta decidual cells Moderate Uncertain
    placenta trophoblastic cells Moderate Uncertain
    prostate glandular cells Strong Uncertain
    rectum glandular cells Strong Uncertain
    salivary gland glandular cells Weak Uncertain
    seminal vesicle glandular cells Moderate Uncertain
    skeletal muscle myocytes Moderate Uncertain
    skin epidermal cells Moderate Uncertain
    small intestine glandular cells Strong Uncertain
    smooth muscle smooth muscle cells Negative Uncertain
    spleen cells in red pulp Moderate Uncertain
    spleen cells in white pulp Moderate Uncertain
    stomach, lower glandular cells Strong Uncertain
    stomach, upper glandular cells Strong Uncertain
    testis cells in seminiferus ducts Moderate Uncertain
    testis Leydig cells Strong Uncertain
    thyroid gland glandular cells Moderate Uncertain
    tonsil germinal center cells Moderate Uncertain
    tonsil non-germinal center cells Moderate Uncertain
    tonsil squamous epithelial cells Moderate Uncertain
    urinary bladder urothelial cells Strong Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Moderate Uncertain
    uterus, pre-menopause cells in endometrial stroma Weak Uncertain
    uterus, pre-menopause glandular cells Moderate Uncertain
    vagina squamous epithelial cells Moderate Uncertain
    vulva/anal skin epidermal cells Moderate Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005887 integral to plasma membrane 19118217 Component
    GO:0005524 ATP binding Function
    GO:0004672 protein kinase activity 12775584 Function
    GO:0019901 protein kinase binding 19118217 Function
    GO:0005005 transmembrane-ephrin receptor activity 19118217 Function
    GO:0032862 activation of Rho GTPase activity 19118217 Process
    GO:0001525 angiogenesis Process
    GO:0007166 cell surface receptor signaling pathway 19118217 Process
    GO:0030336 negative regulation of cell migration 19118217 Process
    GO:0006469 negative regulation of protein kinase activity 19118217 Process
    GO:0018108 peptidyl-tyrosine phosphorylation 12775584 Process
    GO:0045766 positive regulation of angiogenesis Process
    GO:0030335 positive regulation of cell migration Process
    GO:0008284 positive regulation of cell proliferation Process
    GO:0001954 positive regulation of cell-matrix adhesion 19118217 Process
    GO:0051496 positive regulation of stress fiber assembly Process
    GO:0046777 protein autophosphorylation 19118217 Process
    GO:0032314 regulation of Rac GTPase activity 19118217 Process
    GO:0034446 substrate adhesion-dependent cell spreading 19118217 Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084