Gene: ABCA5

  • Entrez Gene ID

  • Symbol

    • ABCA5
  • Synonyms

    • ABC13, EST90625
  • Description

    • ATP-binding cassette, sub-family A (ABC1), member 5
  • Type of Gene

    • protein-coding
  • Chromosome

    • 17
  • Location

    • 17q24.3
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    1.43
    colon
    0.9
    heart
    0.94
    hypothalamus
    1.19
    kidney
    2.08
    liver
    2.58
    lung
    0.94
    ovary
    1.27
    skeletalmuscle
    8.08
    spleen
    0.73
    testes
    1.78
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Strong Uncertain
    appendix glandular cells Moderate Uncertain
    appendix lymphoid tissue Weak Uncertain
    bone marrow hematopoietic cells Strong Uncertain
    breast glandular cells Strong Uncertain
    bronchus respiratory epithelial cells Strong Uncertain
    cerebellum cells in granular layer Strong Uncertain
    cerebellum cells in molecular layer Moderate Uncertain
    cerebellum Purkinje cells Strong Uncertain
    cerebral cortex glial cells Weak Uncertain
    cerebral cortex neuronal cells Moderate Uncertain
    cervix, uterine glandular cells Moderate Uncertain
    cervix, uterine squamous epithelial cells Moderate Uncertain
    colon glandular cells Strong Uncertain
    duodenum glandular cells Strong Uncertain
    epididymis glandular cells Moderate Uncertain
    esophagus squamous epithelial cells Moderate Uncertain
    fallopian tube glandular cells Strong Uncertain
    gall bladder glandular cells Strong Uncertain
    heart muscle myocytes Strong Uncertain
    hippocampus glial cells Weak Uncertain
    hippocampus neuronal cells Moderate Uncertain
    kidney cells in glomeruli Moderate Uncertain
    kidney cells in tubules Strong Uncertain
    lateral ventricle glial cells Moderate Uncertain
    lateral ventricle neuronal cells Moderate Uncertain
    liver bile duct cells Moderate Uncertain
    liver hepatocytes Moderate Uncertain
    lung macrophages Moderate Uncertain
    lung pneumocytes Moderate Uncertain
    lymph node germinal center cells Moderate Uncertain
    lymph node non-germinal center cells Strong Uncertain
    nasopharynx respiratory epithelial cells Strong Uncertain
    oral mucosa squamous epithelial cells Moderate Uncertain
    ovary follicle cells Moderate Uncertain
    ovary ovarian stroma cells Weak Uncertain
    pancreas exocrine glandular cells Moderate Uncertain
    pancreas islets of Langerhans Moderate Uncertain
    parathyroid gland glandular cells Strong Uncertain
    placenta decidual cells Moderate Uncertain
    placenta trophoblastic cells Strong Uncertain
    prostate glandular cells Moderate Uncertain
    rectum glandular cells Strong Uncertain
    salivary gland glandular cells Strong Uncertain
    seminal vesicle glandular cells Moderate Uncertain
    skeletal muscle myocytes Strong Uncertain
    skin epidermal cells Moderate Uncertain
    small intestine glandular cells Strong Uncertain
    smooth muscle smooth muscle cells Moderate Uncertain
    spleen cells in red pulp Moderate Uncertain
    spleen cells in white pulp Moderate Uncertain
    stomach, lower glandular cells Moderate Uncertain
    stomach, upper glandular cells Strong Uncertain
    testis cells in seminiferus ducts Moderate Uncertain
    testis Leydig cells Strong Uncertain
    thyroid gland glandular cells Moderate Uncertain
    tonsil germinal center cells Moderate Uncertain
    tonsil non-germinal center cells Strong Uncertain
    tonsil squamous epithelial cells Strong Uncertain
    urinary bladder urothelial cells Strong Uncertain
    uterus, post-menopause cells in endometrial stroma Weak Uncertain
    uterus, post-menopause glandular cells Strong Uncertain
    uterus, pre-menopause cells in endometrial stroma Weak Uncertain
    uterus, pre-menopause glandular cells Strong Uncertain
    vagina squamous epithelial cells Moderate Uncertain
    vulva/anal skin epidermal cells Moderate Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0000139 Golgi membrane Component
    GO:0016021 integral to membrane Component
    GO:0005770 late endosome 15870284 Component
    GO:0031902 late endosome membrane Component
    GO:0005765 lysosomal membrane Component
    GO:0005764 lysosome 15870284 Component
    GO:0005524 ATP binding Function
    GO:0016887 ATPase activity Function
    GO:0033344 cholesterol efflux Process
    GO:0034375 high-density lipoprotein particle remodeling Process
    GO:0010745 negative regulation of macrophage derived foam cell differentiation Process
    GO:0043691 reverse cholesterol transport Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084