Gene: AATF

  • Entrez Gene ID

  • Symbol

    • AATF
  • Synonyms

    • CHE-1, CHE1, DED
  • Description

    • apoptosis antagonizing transcription factor
  • Type of Gene

    • protein-coding
  • Chromosome

    • 17
  • Location

    • 17q12
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    13.33
    colon
    10.95
    heart
    13.48
    hypothalamus
    17.06
    kidney
    14.1
    liver
    14.55
    lung
    11.19
    ovary
    14.22
    skeletalmuscle
    11.85
    spleen
    20.83
    testes
    17.26
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Strong Uncertain
    appendix glandular cells Strong Uncertain
    appendix lymphoid tissue Strong Uncertain
    breast glandular cells Strong Uncertain
    bronchus respiratory epithelial cells Strong Uncertain
    cerebellum cells in molecular layer Strong Uncertain
    cerebellum Purkinje cells Strong Uncertain
    cerebral cortex glial cells Negative Uncertain
    cerebral cortex neuronal cells Strong Uncertain
    cervix, uterine squamous epithelial cells Moderate Uncertain
    colon glandular cells Strong Uncertain
    duodenum glandular cells Strong Uncertain
    epididymis glandular cells Moderate Uncertain
    esophagus squamous epithelial cells Moderate Uncertain
    fallopian tube glandular cells Strong Uncertain
    heart muscle myocytes Strong Uncertain
    hippocampus glial cells Weak Uncertain
    hippocampus neuronal cells Strong Uncertain
    kidney cells in glomeruli Strong Uncertain
    kidney cells in tubules Moderate Uncertain
    lateral ventricle glial cells Moderate Uncertain
    lateral ventricle neuronal cells Strong Uncertain
    liver hepatocytes Moderate Uncertain
    lung macrophages Strong Uncertain
    lung pneumocytes Strong Uncertain
    lymph node germinal center cells Strong Uncertain
    lymph node non-germinal center cells Strong Uncertain
    nasopharynx respiratory epithelial cells Strong Uncertain
    oral mucosa squamous epithelial cells Strong Uncertain
    ovary ovarian stroma cells Moderate Uncertain
    pancreas exocrine glandular cells Strong Uncertain
    pancreas islets of Langerhans Strong Uncertain
    parathyroid gland glandular cells Weak Uncertain
    placenta decidual cells Strong Uncertain
    placenta trophoblastic cells Strong Uncertain
    prostate glandular cells Moderate Uncertain
    rectum glandular cells Strong Uncertain
    salivary gland glandular cells Strong Uncertain
    seminal vesicle glandular cells Strong Uncertain
    skeletal muscle myocytes Moderate Uncertain
    skin epidermal cells Weak Uncertain
    small intestine glandular cells Strong Uncertain
    smooth muscle smooth muscle cells Moderate Uncertain
    spleen cells in red pulp Strong Uncertain
    spleen cells in white pulp Strong Uncertain
    stomach, lower glandular cells Strong Uncertain
    stomach, upper glandular cells Strong Uncertain
    testis cells in seminiferus ducts Strong Uncertain
    testis Leydig cells Moderate Uncertain
    thyroid gland glandular cells Strong Uncertain
    tonsil germinal center cells Strong Uncertain
    tonsil non-germinal center cells Strong Uncertain
    tonsil squamous epithelial cells Strong Uncertain
    urinary bladder urothelial cells Strong Uncertain
    uterus, post-menopause cells in endometrial stroma Strong Uncertain
    uterus, post-menopause glandular cells Moderate Uncertain
    uterus, pre-menopause cells in endometrial stroma Strong Uncertain
    uterus, pre-menopause glandular cells Moderate Uncertain
    vagina squamous epithelial cells Moderate Uncertain
    vulva/anal skin epidermal cells Moderate Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005813 centrosome 18029348 Component
    GO:0005737 cytoplasm 14627703 Component
    GO:0005925 focal adhesion 18029348 Component
    GO:0005794 Golgi apparatus Component
    GO:0005730 nucleolus 18029348 Component
    GO:0005634 nucleus 10580117 Component
    GO:0043522 leucine zipper domain binding 10580117 Function
    GO:0005515 protein binding 10783144 Function
    GO:0003700 sequence-specific DNA binding transcription factor activity 10580117 Function
    GO:0048156 tau protein binding Function
    GO:0006915 apoptotic process Process
    GO:0007155 cell adhesion Process
    GO:0040016 embryonic cleavage Process
    GO:0008624 induction of apoptosis by extracellular signals Process
    GO:0042985 negative regulation of amyloid precursor protein biosynthetic process Process
    GO:2000378 negative regulation of reactive oxygen species metabolic process 15207272 Process
    GO:0032929 negative regulation of superoxide anion generation 15207272 Process
    GO:0048011 nerve growth factor receptor signaling pathway Process
    GO:0045944 positive regulation of transcription from RNA polymerase II promoter 18049476 Process
    GO:0007346 regulation of mitotic cell cycle Process
    GO:0006974 response to DNA damage stimulus 18049476 Process
    GO:0042254 ribosome biogenesis Process
    GO:0006351 transcription, DNA-dependent Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084