Gene: A1CF

  • Entrez Gene ID

  • Symbol

    • A1CF
  • Synonyms

    • ACF, ACF64, ACF65, APOBEC1CF, ASP
  • Description

    • APOBEC1 complementation factor
  • Type of Gene

    • protein-coding
  • Chromosome

    • 10
  • Location

    • 10q11.23
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0
    colon
    2.39
    heart
    0.17
    hypothalamus
    0.05
    kidney
    7.04
    liver
    42.32
    lung
    0.2
    ovary
    0.16
    skeletalmuscle
    0.1
    spleen
    0.08
    testes
    0
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Moderate Uncertain
    appendix glandular cells Weak Uncertain
    appendix lymphoid tissue Negative Uncertain
    bone marrow hematopoietic cells Weak Uncertain
    breast glandular cells Moderate Uncertain
    bronchus respiratory epithelial cells Moderate Uncertain
    cerebellum cells in granular layer Negative Uncertain
    cerebellum cells in molecular layer Negative Uncertain
    cerebellum Purkinje cells Negative Uncertain
    cerebral cortex glial cells Weak Uncertain
    cerebral cortex neuronal cells Moderate Uncertain
    cervix, uterine glandular cells Weak Uncertain
    cervix, uterine squamous epithelial cells Negative Uncertain
    colon glandular cells Strong Uncertain
    duodenum glandular cells Strong Uncertain
    epididymis glandular cells Weak Uncertain
    esophagus squamous epithelial cells Weak Uncertain
    fallopian tube glandular cells Weak Uncertain
    gall bladder glandular cells Strong Uncertain
    heart muscle myocytes Moderate Uncertain
    hippocampus glial cells Negative Uncertain
    hippocampus neuronal cells Negative Uncertain
    kidney cells in glomeruli Negative Uncertain
    kidney cells in tubules Strong Uncertain
    lateral ventricle glial cells Weak Uncertain
    lateral ventricle neuronal cells Moderate Uncertain
    liver bile duct cells Moderate Uncertain
    liver hepatocytes Strong Uncertain
    lung macrophages Moderate Uncertain
    lung pneumocytes Weak Uncertain
    lymph node germinal center cells Negative Uncertain
    lymph node non-germinal center cells Negative Uncertain
    nasopharynx respiratory epithelial cells Moderate Uncertain
    oral mucosa squamous epithelial cells Moderate Uncertain
    ovary follicle cells Moderate Uncertain
    ovary ovarian stroma cells Negative Uncertain
    pancreas exocrine glandular cells Strong Uncertain
    pancreas islets of Langerhans Negative Uncertain
    parathyroid gland glandular cells Negative Uncertain
    placenta decidual cells Negative Uncertain
    placenta trophoblastic cells Weak Uncertain
    prostate glandular cells Negative Uncertain
    rectum glandular cells Moderate Uncertain
    salivary gland glandular cells Moderate Uncertain
    seminal vesicle glandular cells Moderate Uncertain
    skeletal muscle myocytes Moderate Uncertain
    skin epidermal cells Weak Uncertain
    small intestine glandular cells Strong Uncertain
    smooth muscle smooth muscle cells Moderate Uncertain
    spleen cells in red pulp Negative Uncertain
    spleen cells in white pulp Negative Uncertain
    stomach, lower glandular cells Negative Uncertain
    stomach, upper glandular cells Weak Uncertain
    testis cells in seminiferus ducts Weak Uncertain
    testis Leydig cells Moderate Uncertain
    thyroid gland glandular cells Moderate Uncertain
    tonsil germinal center cells Negative Uncertain
    tonsil non-germinal center cells Negative Uncertain
    tonsil squamous epithelial cells Negative Uncertain
    urinary bladder urothelial cells Weak Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Negative Uncertain
    uterus, pre-menopause cells in endometrial stroma Negative Uncertain
    uterus, pre-menopause glandular cells Negative Uncertain
    vagina squamous epithelial cells Weak Uncertain
    vulva/anal skin epidermal cells Weak Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0030895 apolipoprotein B mRNA editing enzyme complex 10781591 Component
    GO:0005737 cytoplasm 12881431 Component
    GO:0005783 endoplasmic reticulum Component
    GO:0005720 nuclear heterochromatin Component
    GO:0005654 nucleoplasm Component
    GO:0004131 cytosine deaminase activity Function
    GO:0003725 double-stranded RNA binding 11871661 Function
    GO:0003729 mRNA binding Function
    GO:0000166 nucleotide binding Function
    GO:0005515 protein binding 10669759 Function
    GO:0003723 RNA binding 10669759 Function
    GO:0003727 single-stranded RNA binding 11871661 Function
    GO:0016554 cytidine to uridine editing Process
    GO:0010467 gene expression Process
    GO:0016556 mRNA modification Process
    GO:0006397 mRNA processing Process
    GO:0050821 protein stabilization 12881431 Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084