CellFinder · Gene

Gene: KIT

Entrez Gene ID
- 3815 (Go to NCBI)
Symbol
- KIT
Synonyms
- C-Kit, CD117, PBT, SCFR
Description
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Type of Gene
- protein-coding
Chromosome
- 4
Location
- 4q11-q12

RNA Seq ¹

Sample	Expression	RPKM
adipose		0.84
colon		1.11
heart		0.34
hypothalamus		3.06
kidney		2.19
liver		0.07
lung		2.51
ovary		6.69
skeletalmuscle		0.37
spleen		0.57
testes		1.31

Gene Ontology

GO ID	GO term	PubMed	Category
GO:0005737	cytoplasm	18029348	Component
GO:0009897	external side of plasma membrane		Component
GO:0005615	extracellular space	14625290	Component
GO:0016021	integral to membrane		Component
GO:0005634	nucleus	18029348	Component
GO:0005886	plasma membrane		Component
GO:0005524	ATP binding		Function
GO:0019955	cytokine binding		Function
GO:0046872	metal ion binding		Function
GO:0002020	protease binding		Function
GO:0005515	protein binding	17662946	Function
GO:0042803	protein homodimerization activity		Function
GO:0004713	protein tyrosine kinase activity	1717985	Function
GO:0004716	receptor signaling protein tyrosine kinase activity	9438854	Function
GO:0005020	stem cell factor receptor activity		Function
GO:0004714	transmembrane receptor protein tyrosine kinase activity		Function
GO:0031532	actin cytoskeleton reorganization	1721869	Process
GO:0000187	activation of MAPK activity		Process
GO:0060326	cell chemotaxis	1721869	Process
GO:0097067	cellular response to thyroid hormone stimulus		Process
GO:0019221	cytokine-mediated signaling pathway		Process
GO:0002371	dendritic cell cytokine production		Process
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound		Process
GO:0048565	digestive tract development		Process
GO:0035162	embryonic hemopoiesis		Process
GO:0030218	erythrocyte differentiation		Process
GO:0038162	erythropoietin-mediated signaling pathway		Process
GO:0038093	Fc receptor signaling pathway		Process
GO:0035234	germ cell programmed cell death		Process
GO:0006687	glycosphingolipid metabolic process		Process
GO:0030097	hemopoiesis	16129412	Process
GO:0002327	immature B cell differentiation		Process
GO:0006954	inflammatory response		Process
GO:0007243	intracellular protein kinase cascade		Process
GO:0038109	Kit signaling pathway	17662946	Process
GO:0030032	lamellipodium assembly		Process
GO:0002320	lymphoid progenitor cell differentiation		Process
GO:0008584	male gonad development	17848411	Process
GO:0002551	mast cell chemotaxis		Process
GO:0032762	mast cell cytokine production		Process
GO:0043303	mast cell degranulation		Process
GO:0060374	mast cell differentiation		Process
GO:0060374	mast cell differentiation	16129412	Process
GO:0070662	mast cell proliferation		Process
GO:0035855	megakaryocyte development		Process
GO:0097326	melanocyte adhesion		Process
GO:0030318	melanocyte differentiation		Process
GO:0030318	melanocyte differentiation		Process
GO:0097324	melanocyte migration		Process
GO:0002318	myeloid progenitor cell differentiation		Process
GO:0043069	negative regulation of programmed cell death		Process
GO:0001541	ovarian follicle development		Process
GO:0018108	peptidyl-tyrosine phosphorylation		Process
GO:0043473	pigmentation		Process
GO:0008284	positive regulation of cell proliferation		Process
GO:0010628	positive regulation of gene expression		Process
GO:0046427	positive regulation of JAK-STAT cascade		Process
GO:0043410	positive regulation of MAPK cascade		Process
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	16129412	Process
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	16129412	Process
GO:0010863	positive regulation of phospholipase C activity	16129412	Process
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity		Process
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein		Process
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein		Process
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein		Process
GO:0046777	protein autophosphorylation		Process
GO:0042127	regulation of cell proliferation	16129412	Process
GO:0008360	regulation of cell shape		Process
GO:0048070	regulation of developmental pigmentation		Process
GO:0009314	response to radiation		Process
GO:0007165	signal transduction	9990072	Process
GO:0023014	signal transduction by phosphorylation	9438854	Process
GO:0007286	spermatid development		Process
GO:0007283	spermatogenesis		Process
GO:0007283	spermatogenesis	16129412	Process
GO:0048863	stem cell differentiation		Process
GO:0019827	stem cell maintenance		Process
GO:0030217	T cell differentiation		Process

Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084

Gene: KIT

Entrez Gene ID

Symbol

Synonyms

Description

Type of Gene

Chromosome

Location

RNA Seq 1

Gene Ontology

RNA Seq ¹