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Entrez Gene ID
- 387 (Go to NCBI)
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Symbol
- RHOA
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Synonyms
- ARH12, ARHA, RHO12, RHOH12
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Description
- ras homolog family member A
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Type of Gene
- protein-coding
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Chromosome
- 3
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Location
- 3p21.3
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RNA Seq 1
Sample Expression RPKM adipose 65.99 colon 28.28 heart 31.69 hypothalamus 27.3 kidney 31.44 liver 25.35 lung 56.68 ovary 17.5 skeletalmuscle 24.32 spleen 55.1 testes 41.94 -
Protein
Tissue Cell type Staining level Reliability adrenal gland glandular cells Moderate Uncertain appendix glandular cells Weak Uncertain appendix lymphoid tissue Weak Uncertain bone marrow hematopoietic cells Weak Uncertain breast glandular cells Weak Uncertain bronchus respiratory epithelial cells Weak Uncertain cerebellum cells in granular layer Weak Uncertain cerebellum cells in molecular layer Moderate Uncertain cerebellum Purkinje cells Weak Uncertain cerebral cortex glial cells Moderate Uncertain cerebral cortex neuronal cells Moderate Uncertain cervix, uterine glandular cells Weak Uncertain cervix, uterine squamous epithelial cells Negative Uncertain colon glandular cells Weak Uncertain duodenum glandular cells Moderate Uncertain epididymis glandular cells Weak Uncertain esophagus squamous epithelial cells Negative Uncertain fallopian tube glandular cells Weak Uncertain gall bladder glandular cells Weak Uncertain heart muscle myocytes Negative Uncertain hippocampus glial cells Moderate Uncertain hippocampus neuronal cells Moderate Uncertain kidney cells in glomeruli Weak Uncertain kidney cells in tubules Weak Uncertain lateral ventricle glial cells Moderate Uncertain liver bile duct cells Negative Uncertain liver hepatocytes Negative Uncertain lung macrophages Moderate Uncertain lung pneumocytes Weak Uncertain lymph node germinal center cells Weak Uncertain lymph node non-germinal center cells Moderate Uncertain nasopharynx respiratory epithelial cells Moderate Uncertain oral mucosa squamous epithelial cells Negative Uncertain ovary ovarian stroma cells Weak Uncertain pancreas exocrine glandular cells Weak Uncertain pancreas islets of Langerhans Moderate Uncertain parathyroid gland glandular cells Weak Uncertain placenta decidual cells Weak Uncertain placenta trophoblastic cells Moderate Uncertain prostate glandular cells Weak Uncertain rectum glandular cells Moderate Uncertain salivary gland glandular cells Weak Uncertain seminal vesicle glandular cells Weak Uncertain skeletal muscle myocytes Negative Uncertain skin epidermal cells Negative Uncertain small intestine glandular cells Weak Uncertain smooth muscle smooth muscle cells Negative Uncertain spleen cells in red pulp Weak Uncertain spleen cells in white pulp Weak Uncertain stomach, lower glandular cells Moderate Uncertain stomach, upper glandular cells Moderate Uncertain testis cells in seminiferus ducts Moderate Uncertain testis Leydig cells Weak Uncertain thyroid gland glandular cells Moderate Uncertain tonsil germinal center cells Weak Uncertain tonsil non-germinal center cells Moderate Uncertain tonsil squamous epithelial cells Weak Uncertain urinary bladder urothelial cells Moderate Uncertain uterus, post-menopause cells in endometrial stroma Weak Uncertain uterus, post-menopause glandular cells Weak Uncertain uterus, pre-menopause cells in endometrial stroma Weak Uncertain uterus, pre-menopause glandular cells Weak Uncertain vagina squamous epithelial cells Negative Uncertain vulva/anal skin epidermal cells Negative Uncertain -
Gene Ontology
GO ID GO term PubMed Category GO:0043296 apical junction complex Component GO:0005938 cell cortex 16103226 Component GO:0030054 cell junction Component GO:0032154 cleavage furrow Component GO:0005856 cytoskeleton Component GO:0005829 cytosol Component GO:0030027 lamellipodium Component GO:0030496 midbody Component GO:0005739 mitochondrion Component GO:0005634 nucleus Component GO:0005886 plasma membrane Component GO:0032587 ruffle membrane Component GO:0005525 GTP binding Function GO:0003924 GTPase activity 10436159 Function GO:0017022 myosin binding 15644318 Function GO:0005515 protein binding 10051605 Function GO:0030036 actin cytoskeleton organization 10436159 Process GO:0030521 androgen receptor signaling pathway Process GO:0043297 apical junction assembly Process GO:0007411 axon guidance Process GO:0007596 blood coagulation Process GO:0007160 cell-matrix adhesion Process GO:0036089 cleavage furrow formation 16103226 Process GO:0050771 negative regulation of axonogenesis Process GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway Process GO:0043524 negative regulation of neuron apoptotic process Process GO:0048011 nerve growth factor receptor signaling pathway Process GO:0043931 ossification involved in bone maturation Process GO:0048015 phosphatidylinositol-mediated signaling Process GO:0030168 platelet activation Process GO:0050772 positive regulation of axonogenesis Process GO:0071777 positive regulation of cell cycle cytokinesis 16103226 Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 12761501 Process GO:0045666 positive regulation of neuron differentiation 17488780 Process GO:0042346 positive regulation of NF-kappaB import into nucleus 12761501 Process GO:0051496 positive regulation of stress fiber assembly 15467718 Process GO:0050770 regulation of axonogenesis Process GO:0030334 regulation of cell migration 19934221 Process GO:0033688 regulation of osteoblast proliferation Process GO:0051056 regulation of small GTPase mediated signal transduction Process GO:0006357 regulation of transcription from RNA polymerase II promoter Process GO:0007266 Rho protein signal transduction 10436159 Process GO:0007519 skeletal muscle tissue development Process GO:0007264 small GTPase mediated signal transduction Process GO:0090307 spindle assembly involved in mitosis 19635168 Process GO:0043149 stress fiber assembly Process GO:0061383 trabecula morphogenesis Process GO:0007179 transforming growth factor beta receptor signaling pathway Process GO:0019048 virus-host interaction Process
- Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084