Gene: PGF

  • Entrez Gene ID

  • Symbol

    • PGF
  • Synonyms

    • D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760
  • Description

    • placental growth factor
  • Type of Gene

    • protein-coding
  • Chromosome

    • 14
  • Location

    • 14q24.3
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.28
    colon
    0.42
    heart
    1.58
    hypothalamus
    1.07
    kidney
    0.28
    liver
    0.87
    lung
    0.36
    ovary
    0.6
    skeletalmuscle
    0.51
    spleen
    0.29
    testes
    0.27
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Strong Uncertain
    appendix glandular cells Moderate Uncertain
    appendix lymphoid tissue Weak Uncertain
    bone marrow hematopoietic cells Negative Uncertain
    breast glandular cells Moderate Uncertain
    bronchus respiratory epithelial cells Weak Uncertain
    cerebellum cells in granular layer Negative Uncertain
    cerebellum cells in molecular layer Negative Uncertain
    cerebellum Purkinje cells Negative Uncertain
    cerebral cortex glial cells Strong Uncertain
    cerebral cortex neuronal cells Negative Uncertain
    cervix, uterine glandular cells Moderate Uncertain
    cervix, uterine squamous epithelial cells Weak Uncertain
    colon glandular cells Strong Uncertain
    duodenum glandular cells Strong Uncertain
    epididymis glandular cells Strong Uncertain
    esophagus squamous epithelial cells Negative Uncertain
    fallopian tube glandular cells Strong Uncertain
    gall bladder glandular cells Strong Uncertain
    heart muscle myocytes Weak Uncertain
    hippocampus glial cells Moderate Uncertain
    hippocampus neuronal cells Negative Uncertain
    kidney cells in glomeruli Weak Uncertain
    kidney cells in tubules Moderate Uncertain
    lateral ventricle glial cells Strong Uncertain
    lateral ventricle neuronal cells Negative Uncertain
    liver bile duct cells Weak Uncertain
    liver hepatocytes Moderate Uncertain
    lung macrophages Moderate Uncertain
    lung pneumocytes Weak Uncertain
    lymph node germinal center cells Weak Uncertain
    lymph node non-germinal center cells Moderate Uncertain
    nasopharynx respiratory epithelial cells Moderate Uncertain
    oral mucosa squamous epithelial cells Moderate Uncertain
    ovary follicle cells Moderate Uncertain
    ovary ovarian stroma cells Negative Uncertain
    pancreas exocrine glandular cells Strong Uncertain
    pancreas islets of Langerhans Weak Uncertain
    parathyroid gland glandular cells Strong Uncertain
    placenta trophoblastic cells Strong Uncertain
    prostate glandular cells Moderate Uncertain
    rectum glandular cells Moderate Uncertain
    salivary gland glandular cells Negative Uncertain
    seminal vesicle glandular cells Moderate Uncertain
    skeletal muscle myocytes Weak Uncertain
    skin epidermal cells Weak Uncertain
    small intestine glandular cells Strong Uncertain
    smooth muscle smooth muscle cells Moderate Uncertain
    spleen cells in red pulp Negative Uncertain
    spleen cells in white pulp Negative Uncertain
    stomach, lower glandular cells Strong Uncertain
    stomach, upper glandular cells Moderate Uncertain
    testis cells in seminiferus ducts Moderate Uncertain
    testis Leydig cells Strong Uncertain
    thyroid gland glandular cells Moderate Uncertain
    tonsil germinal center cells Weak Uncertain
    tonsil non-germinal center cells Weak Uncertain
    tonsil squamous epithelial cells Moderate Uncertain
    urinary bladder urothelial cells Moderate Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Weak Uncertain
    uterus, pre-menopause cells in endometrial stroma Negative Uncertain
    uterus, pre-menopause glandular cells Moderate Uncertain
    vagina squamous epithelial cells Negative Uncertain
    vulva/anal skin epidermal cells Moderate Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005576 extracellular region Component
    GO:0005615 extracellular space Component
    GO:0016020 membrane Component
    GO:0008083 growth factor activity Function
    GO:0008201 heparin binding Function
    GO:0046982 protein heterodimerization activity Function
    GO:0042803 protein homodimerization activity Function
    GO:0001525 angiogenesis Process
    GO:0001658 branching involved in ureteric bud morphogenesis Process
    GO:0030154 cell differentiation Process
    GO:0007267 cell-cell signaling 9467961 Process
    GO:0032870 cellular response to hormone stimulus Process
    GO:0007565 female pregnancy Process
    GO:0051781 positive regulation of cell division Process
    GO:0008284 positive regulation of cell proliferation Process
    GO:0001938 positive regulation of endothelial cell proliferation Process
    GO:0060688 regulation of morphogenesis of a branching structure Process
    GO:0042493 response to drug Process
    GO:0001666 response to hypoxia Process
    GO:0007165 signal transduction 9467961 Process
    GO:0048010 vascular endothelial growth factor receptor signaling pathway Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084