Gene: AACS

  • Entrez Gene ID

  • Symbol

    • AACS
  • Synonyms

    • ACSF1, SUR-5
  • Description

    • acetoacetyl-CoA synthetase
  • Type of Gene

    • protein-coding
  • Chromosome

    • 12
  • Location

    • 12q24.31
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    3.85
    colon
    2.75
    heart
    1.56
    hypothalamus
    4.01
    kidney
    2.47
    liver
    0.55
    lung
    1.09
    ovary
    0.94
    skeletalmuscle
    0.28
    spleen
    1.38
    testes
    2.96
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Negative Uncertain
    appendix glandular cells Negative Uncertain
    appendix lymphoid tissue Negative Uncertain
    bone marrow hematopoietic cells Moderate Uncertain
    breast glandular cells Weak Uncertain
    bronchus respiratory epithelial cells Negative Uncertain
    cerebellum cells in granular layer Negative Uncertain
    cerebellum cells in molecular layer Negative Uncertain
    cerebellum Purkinje cells Negative Uncertain
    cerebral cortex glial cells Negative Uncertain
    cerebral cortex neuronal cells Negative Uncertain
    cervix, uterine glandular cells Negative Uncertain
    cervix, uterine squamous epithelial cells Negative Uncertain
    colon glandular cells Negative Uncertain
    duodenum glandular cells Negative Uncertain
    epididymis glandular cells Negative Uncertain
    esophagus squamous epithelial cells Negative Uncertain
    fallopian tube glandular cells Negative Uncertain
    gall bladder glandular cells Negative Uncertain
    heart muscle myocytes Moderate Uncertain
    hippocampus glial cells Negative Uncertain
    hippocampus neuronal cells Negative Uncertain
    kidney cells in glomeruli Negative Uncertain
    kidney cells in tubules Moderate Uncertain
    lateral ventricle glial cells Negative Uncertain
    lateral ventricle neuronal cells Negative Uncertain
    liver bile duct cells Negative Uncertain
    liver hepatocytes Negative Uncertain
    lung macrophages Weak Uncertain
    lung pneumocytes Negative Uncertain
    lymph node germinal center cells Negative Uncertain
    lymph node non-germinal center cells Moderate Uncertain
    nasopharynx respiratory epithelial cells Negative Uncertain
    oral mucosa squamous epithelial cells Negative Uncertain
    ovary ovarian stroma cells Negative Uncertain
    pancreas exocrine glandular cells Negative Uncertain
    pancreas islets of Langerhans Moderate Uncertain
    parathyroid gland glandular cells Negative Uncertain
    placenta decidual cells Negative Uncertain
    placenta trophoblastic cells Negative Uncertain
    prostate glandular cells Negative Uncertain
    rectum glandular cells Negative Uncertain
    salivary gland glandular cells Negative Uncertain
    seminal vesicle glandular cells Negative Uncertain
    skeletal muscle myocytes Moderate Uncertain
    skin epidermal cells Weak Uncertain
    small intestine glandular cells Moderate Uncertain
    smooth muscle smooth muscle cells Negative Uncertain
    spleen cells in red pulp Negative Uncertain
    spleen cells in white pulp Negative Uncertain
    stomach, lower glandular cells Negative Uncertain
    stomach, upper glandular cells Negative Uncertain
    testis cells in seminiferus ducts Negative Uncertain
    testis Leydig cells Weak Uncertain
    thyroid gland glandular cells Negative Uncertain
    tonsil germinal center cells Negative Uncertain
    tonsil non-germinal center cells Moderate Uncertain
    tonsil squamous epithelial cells Negative Uncertain
    urinary bladder urothelial cells Negative Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Weak Uncertain
    uterus, pre-menopause cells in endometrial stroma Negative Uncertain
    uterus, pre-menopause glandular cells Negative Uncertain
    vagina squamous epithelial cells Negative Uncertain
    vulva/anal skin epidermal cells Negative Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005829 cytosol Component
    GO:0030729 acetoacetate-CoA ligase activity Function
    GO:0005524 ATP binding Function
    GO:0047760 butyrate-CoA ligase activity Function
    GO:0060612 adipose tissue development Process
    GO:0071397 cellular response to cholesterol Process
    GO:0071333 cellular response to glucose stimulus Process
    GO:0071394 cellular response to testosterone stimulus Process
    GO:0006631 fatty acid metabolic process Process
    GO:0001889 liver development Process
    GO:0032024 positive regulation of insulin secretion Process
    GO:0042493 response to drug Process
    GO:0045471 response to ethanol Process
    GO:0007584 response to nutrient Process
    GO:0034201 response to oleic acid Process
    GO:0010243 response to organic nitrogen Process
    GO:0014074 response to purine-containing compound Process
    GO:0042594 response to starvation Process
    GO:0050872 white fat cell differentiation Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084