Gene: ACTC1

  • Entrez Gene ID

  • Symbol

    • ACTC1
  • Synonyms

    • ACTC, ASD5, CMD1R, CMH11, LVNC4
  • Description

    • actin, alpha, cardiac muscle 1
  • Type of Gene

    • protein-coding
  • Chromosome

    • 15
  • Location

    • 15q14
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.11
    colon
    0.06
    heart
    310.07
    hypothalamus
    0.42
    kidney
    0.31
    liver
    0
    lung
    0.21
    ovary
    0.03
    skeletalmuscle
    14.69
    spleen
    0.08
    testes
    1.09
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Negative Supportive
    appendix glandular cells Negative Supportive
    appendix lymphoid tissue Negative Supportive
    bone marrow hematopoietic cells Negative Supportive
    breast glandular cells Negative Supportive
    bronchus respiratory epithelial cells Negative Supportive
    cerebellum cells in granular layer Negative Supportive
    cerebellum cells in molecular layer Negative Supportive
    cerebellum Purkinje cells Negative Supportive
    cerebral cortex glial cells Negative Supportive
    cerebral cortex neuronal cells Weak Supportive
    cervix, uterine glandular cells Negative Supportive
    cervix, uterine squamous epithelial cells Negative Supportive
    colon glandular cells Negative Supportive
    duodenum glandular cells Weak Supportive
    epididymis glandular cells Weak Supportive
    esophagus squamous epithelial cells Negative Supportive
    fallopian tube glandular cells Negative Supportive
    gall bladder glandular cells Moderate Supportive
    heart muscle myocytes Strong Supportive
    hippocampus glial cells Negative Supportive
    hippocampus neuronal cells Negative Supportive
    kidney cells in glomeruli Negative Supportive
    kidney cells in tubules Negative Supportive
    lateral ventricle glial cells Negative Supportive
    lateral ventricle neuronal cells Negative Supportive
    liver bile duct cells Negative Supportive
    liver hepatocytes Negative Supportive
    lung macrophages Moderate Supportive
    lung pneumocytes Negative Supportive
    lymph node germinal center cells Negative Supportive
    lymph node non-germinal center cells Negative Supportive
    nasopharynx respiratory epithelial cells Negative Supportive
    oral mucosa squamous epithelial cells Negative Supportive
    ovary follicle cells Negative Supportive
    ovary ovarian stroma cells Negative Supportive
    pancreas exocrine glandular cells Weak Supportive
    pancreas islets of Langerhans Negative Supportive
    parathyroid gland glandular cells Negative Supportive
    placenta decidual cells Negative Supportive
    placenta trophoblastic cells Weak Supportive
    prostate glandular cells Negative Supportive
    rectum glandular cells Negative Supportive
    salivary gland glandular cells Weak Supportive
    seminal vesicle glandular cells Negative Supportive
    skeletal muscle myocytes Moderate Supportive
    skin epidermal cells Negative Supportive
    small intestine glandular cells Weak Supportive
    smooth muscle smooth muscle cells Strong Supportive
    spleen cells in red pulp Negative Supportive
    spleen cells in white pulp Negative Supportive
    stomach, lower glandular cells Negative Supportive
    stomach, upper glandular cells Weak Supportive
    testis cells in seminiferus ducts Negative Supportive
    testis Leydig cells Negative Supportive
    thyroid gland glandular cells Weak Supportive
    tonsil germinal center cells Negative Supportive
    tonsil non-germinal center cells Negative Supportive
    tonsil squamous epithelial cells Negative Supportive
    urinary bladder urothelial cells Negative Supportive
    uterus, post-menopause cells in endometrial stroma Negative Supportive
    uterus, post-menopause glandular cells Negative Supportive
    uterus, pre-menopause cells in endometrial stroma Negative Supportive
    uterus, pre-menopause glandular cells Negative Supportive
    vagina squamous epithelial cells Negative Supportive
    vulva/anal skin epidermal cells Weak Supportive
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005884 actin filament 16611632 Component
    GO:0042643 actomyosin, actin part 16611632 Component
    GO:0005737 cytoplasm Component
    GO:0005829 cytosol Component
    GO:0031674 I band Component
    GO:0030017 sarcomere 16288873 Component
    GO:0005524 ATP binding 16611632 Function
    GO:0016887 ATPase activity 16611632 Function
    GO:0017022 myosin binding 19799913 Function
    GO:0017022 myosin binding 16611632 Function
    GO:0030048 actin filament-based movement 16611632 Process
    GO:0033275 actin-myosin filament sliding 19799913 Process
    GO:0031032 actomyosin structure organization Process
    GO:0006915 apoptotic process Process
    GO:0006200 ATP catabolic process 16611632 Process
    GO:0060048 cardiac muscle contraction Process
    GO:0055008 cardiac muscle tissue morphogenesis Process
    GO:0055003 cardiac myofibril assembly Process
    GO:0060047 heart contraction 17611253 Process
    GO:0030049 muscle filament sliding Process
    GO:0042493 response to drug Process
    GO:0045471 response to ethanol Process
    GO:0030240 skeletal muscle thin filament assembly Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084