Gene: LEFTY2

  • Entrez Gene ID

  • Symbol

    • LEFTY2
  • Synonyms

    • EBAF, LEFTA, LEFTYA, TGFB4
  • Description

    • left-right determination factor 2
  • Type of Gene

    • protein-coding
  • Chromosome

    • 1
  • Location

    • 1q42.1
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.02
    colon
    0
    heart
    0.1
    hypothalamus
    0.09
    kidney
    0.02
    liver
    0
    lung
    0.1
    ovary
    3.12
    skeletalmuscle
    0
    spleen
    0.04
    testes
    0.54
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Moderate Uncertain
    appendix glandular cells Moderate Uncertain
    appendix lymphoid tissue Weak Uncertain
    bone marrow hematopoietic cells Weak Uncertain
    breast glandular cells Weak Uncertain
    bronchus respiratory epithelial cells Weak Uncertain
    cerebellum cells in granular layer Weak Uncertain
    cerebellum cells in molecular layer Negative Uncertain
    cerebellum Purkinje cells Negative Uncertain
    cerebral cortex glial cells Negative Uncertain
    cerebral cortex neuronal cells Negative Uncertain
    cervix, uterine glandular cells Negative Uncertain
    cervix, uterine squamous epithelial cells Weak Uncertain
    colon glandular cells Moderate Uncertain
    duodenum glandular cells Strong Uncertain
    epididymis glandular cells Weak Uncertain
    esophagus squamous epithelial cells Moderate Uncertain
    fallopian tube glandular cells Negative Uncertain
    gall bladder glandular cells Strong Uncertain
    heart muscle myocytes Weak Uncertain
    hippocampus glial cells Negative Uncertain
    hippocampus neuronal cells Negative Uncertain
    kidney cells in glomeruli Moderate Uncertain
    kidney cells in tubules Moderate Uncertain
    lateral ventricle glial cells Weak Uncertain
    lateral ventricle neuronal cells Negative Uncertain
    liver bile duct cells Weak Uncertain
    liver hepatocytes Negative Uncertain
    lung macrophages Strong Uncertain
    lung pneumocytes Weak Uncertain
    lymph node germinal center cells Moderate Uncertain
    lymph node non-germinal center cells Strong Uncertain
    nasopharynx respiratory epithelial cells Weak Uncertain
    oral mucosa squamous epithelial cells Negative Uncertain
    ovary ovarian stroma cells Negative Uncertain
    pancreas exocrine glandular cells Moderate Uncertain
    pancreas islets of Langerhans Negative Uncertain
    parathyroid gland glandular cells Weak Uncertain
    placenta decidual cells Negative Uncertain
    placenta trophoblastic cells Weak Uncertain
    prostate glandular cells Weak Uncertain
    rectum glandular cells Moderate Uncertain
    salivary gland glandular cells Weak Uncertain
    seminal vesicle glandular cells Negative Uncertain
    skeletal muscle myocytes Moderate Uncertain
    skin epidermal cells Negative Uncertain
    small intestine glandular cells Strong Uncertain
    smooth muscle smooth muscle cells Weak Uncertain
    spleen cells in red pulp Moderate Uncertain
    spleen cells in white pulp Moderate Uncertain
    stomach, lower glandular cells Moderate Uncertain
    stomach, upper glandular cells Moderate Uncertain
    testis cells in seminiferus ducts Negative Uncertain
    testis Leydig cells Weak Uncertain
    thyroid gland glandular cells Weak Uncertain
    tonsil germinal center cells Moderate Uncertain
    tonsil non-germinal center cells Strong Uncertain
    tonsil squamous epithelial cells Moderate Uncertain
    urinary bladder urothelial cells Moderate Uncertain
    uterus, post-menopause cells in endometrial stroma Moderate Uncertain
    uterus, post-menopause glandular cells Weak Uncertain
    uterus, pre-menopause cells in endometrial stroma Weak Uncertain
    uterus, pre-menopause glandular cells Negative Uncertain
    vagina squamous epithelial cells Negative Uncertain
    vulva/anal skin epidermal cells Weak Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005576 extracellular region Component
    GO:0005615 extracellular space Component
    GO:0031093 platelet alpha granule lumen Component
    GO:0005125 cytokine activity Function
    GO:0008083 growth factor activity Function
    GO:0005160 transforming growth factor beta receptor binding Function
    GO:0007596 blood coagulation Process
    GO:0016049 cell growth Process
    GO:0007275 multicellular organismal development Process
    GO:0030168 platelet activation Process
    GO:0002576 platelet degranulation Process
    GO:0007179 transforming growth factor beta receptor signaling pathway 9153275 Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084