Gene: AAAS

  • Entrez Gene ID

  • Symbol

    • AAAS
  • Synonyms

    • AAA, AAASb, ADRACALA, ADRACALIN, ALADIN
  • Description

    • achalasia, adrenocortical insufficiency, alacrimia
  • Type of Gene

    • protein-coding
  • Chromosome

    • 12
  • Location

    • 12q13
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.68
    colon
    0.98
    heart
    0.79
    hypothalamus
    0.78
    kidney
    0.92
    liver
    0.77
    lung
    0.63
    ovary
    0.47
    skeletalmuscle
    0.55
    spleen
    1.06
    testes
    1.02
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Strong Uncertain
    appendix glandular cells Negative Uncertain
    appendix lymphoid tissue Negative Uncertain
    bone marrow hematopoietic cells Moderate Uncertain
    breast glandular cells Moderate Uncertain
    bronchus respiratory epithelial cells Negative Uncertain
    cerebellum cells in granular layer Strong Uncertain
    cerebellum cells in molecular layer Negative Uncertain
    cerebellum Purkinje cells Moderate Uncertain
    cerebral cortex glial cells Weak Uncertain
    cerebral cortex neuronal cells Weak Uncertain
    cervix, uterine glandular cells Negative Uncertain
    cervix, uterine squamous epithelial cells Negative Uncertain
    colon glandular cells Negative Uncertain
    duodenum glandular cells Weak Uncertain
    epididymis glandular cells Moderate Uncertain
    esophagus squamous epithelial cells Negative Uncertain
    fallopian tube glandular cells Negative Uncertain
    gall bladder glandular cells Negative Uncertain
    heart muscle myocytes Moderate Uncertain
    hippocampus glial cells Weak Uncertain
    hippocampus neuronal cells Strong Uncertain
    kidney cells in glomeruli Weak Uncertain
    kidney cells in tubules Strong Uncertain
    lateral ventricle glial cells Weak Uncertain
    lateral ventricle neuronal cells Weak Uncertain
    liver bile duct cells Negative Uncertain
    liver hepatocytes Moderate Uncertain
    lung macrophages Negative Uncertain
    lung pneumocytes Negative Uncertain
    lymph node germinal center cells Weak Uncertain
    lymph node non-germinal center cells Strong Uncertain
    nasopharynx respiratory epithelial cells Negative Uncertain
    oral mucosa squamous epithelial cells Weak Uncertain
    ovary ovarian stroma cells Moderate Uncertain
    pancreas exocrine glandular cells Negative Uncertain
    pancreas islets of Langerhans Negative Uncertain
    parathyroid gland glandular cells Negative Uncertain
    placenta trophoblastic cells Strong Uncertain
    prostate glandular cells Weak Uncertain
    rectum glandular cells Weak Uncertain
    salivary gland glandular cells Moderate Uncertain
    seminal vesicle glandular cells Moderate Uncertain
    skeletal muscle myocytes Moderate Uncertain
    skin epidermal cells Weak Uncertain
    small intestine glandular cells Negative Uncertain
    smooth muscle smooth muscle cells Moderate Uncertain
    spleen cells in red pulp Moderate Uncertain
    spleen cells in white pulp Strong Uncertain
    stomach, lower glandular cells Negative Uncertain
    stomach, upper glandular cells Negative Uncertain
    testis cells in seminiferus ducts Strong Uncertain
    testis Leydig cells Moderate Uncertain
    thyroid gland glandular cells Strong Uncertain
    tonsil germinal center cells Moderate Uncertain
    tonsil non-germinal center cells Strong Uncertain
    tonsil squamous epithelial cells Negative Uncertain
    urinary bladder urothelial cells Negative Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Negative Uncertain
    uterus, pre-menopause cells in endometrial stroma Moderate Uncertain
    uterus, pre-menopause glandular cells Negative Uncertain
    vagina squamous epithelial cells Negative Uncertain
    vulva/anal skin epidermal cells Negative Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005813 centrosome 18029348 Component
    GO:0005737 cytoplasm 18029348 Component
    GO:0005635 nuclear envelope Component
    GO:0031965 nuclear membrane 18029348 Component
    GO:0005643 nuclear pore 12730363 Component
    GO:0005643 nuclear pore 12730363 Component
    GO:0005730 nucleolus 18029348 Component
    GO:0005634 nucleus 18029348 Component
    GO:0003674 molecular_function Function
    GO:0005975 carbohydrate metabolic process Process
    GO:0019221 cytokine-mediated signaling pathway Process
    GO:0015758 glucose transport Process
    GO:0008645 hexose transport Process
    GO:0006913 nucleocytoplasmic transport 12730363 Process
    GO:0010827 regulation of glucose transport Process
    GO:0046822 regulation of nucleocytoplasmic transport 12730363 Process
    GO:0044281 small molecule metabolic process Process
    GO:0055085 transmembrane transport Process
    GO:0016032 viral reproduction Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084