Gene: EOMES

  • Entrez Gene ID

  • Symbol

    • EOMES
  • Synonyms

    • TBR2
  • Description

    • eomesodermin
  • Type of Gene

    • protein-coding
  • Chromosome

    • 3
  • Location

    • 3p24.1
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.36
    colon
    0.01
    heart
    0.16
    hypothalamus
    0.08
    kidney
    0.05
    liver
    0.12
    lung
    1.02
    ovary
    0.15
    skeletalmuscle
    0.03
    spleen
    4.11
    testes
    0.1
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Moderate Uncertain
    appendix glandular cells Moderate Uncertain
    appendix lymphoid tissue Negative Uncertain
    bone marrow hematopoietic cells Weak Uncertain
    breast glandular cells Moderate Uncertain
    bronchus respiratory epithelial cells Moderate Uncertain
    cerebellum cells in granular layer Moderate Uncertain
    cerebellum cells in molecular layer Negative Uncertain
    cerebellum Purkinje cells Negative Uncertain
    cerebral cortex glial cells Moderate Uncertain
    cerebral cortex neuronal cells Weak Uncertain
    cervix, uterine glandular cells Weak Uncertain
    cervix, uterine squamous epithelial cells Negative Uncertain
    colon glandular cells Weak Uncertain
    duodenum glandular cells Weak Uncertain
    epididymis glandular cells Moderate Uncertain
    esophagus squamous epithelial cells Moderate Uncertain
    fallopian tube glandular cells Moderate Uncertain
    gall bladder glandular cells Moderate Uncertain
    heart muscle myocytes Strong Uncertain
    hippocampus glial cells Moderate Uncertain
    hippocampus neuronal cells Moderate Uncertain
    kidney cells in glomeruli Negative Uncertain
    kidney cells in tubules Strong Uncertain
    lateral ventricle glial cells Weak Uncertain
    lateral ventricle neuronal cells Weak Uncertain
    liver bile duct cells Negative Uncertain
    liver hepatocytes Negative Uncertain
    lung macrophages Moderate Uncertain
    lung pneumocytes Weak Uncertain
    lymph node germinal center cells Negative Uncertain
    lymph node non-germinal center cells Negative Uncertain
    nasopharynx respiratory epithelial cells Moderate Uncertain
    oral mucosa squamous epithelial cells Negative Uncertain
    ovary ovarian stroma cells Negative Uncertain
    pancreas exocrine glandular cells Moderate Uncertain
    pancreas islets of Langerhans Weak Uncertain
    parathyroid gland glandular cells Strong Uncertain
    placenta decidual cells Moderate Uncertain
    placenta trophoblastic cells Weak Uncertain
    prostate glandular cells Moderate Uncertain
    rectum glandular cells Moderate Uncertain
    salivary gland glandular cells Moderate Uncertain
    seminal vesicle glandular cells Weak Uncertain
    skeletal muscle myocytes Moderate Uncertain
    skin epidermal cells Negative Uncertain
    small intestine glandular cells Moderate Uncertain
    smooth muscle smooth muscle cells Negative Uncertain
    spleen cells in red pulp Weak Uncertain
    spleen cells in white pulp Weak Uncertain
    stomach, lower glandular cells Moderate Uncertain
    stomach, upper glandular cells Moderate Uncertain
    testis cells in seminiferus ducts Moderate Uncertain
    testis Leydig cells Moderate Uncertain
    thyroid gland glandular cells Moderate Uncertain
    tonsil germinal center cells Negative Uncertain
    tonsil non-germinal center cells Weak Uncertain
    tonsil squamous epithelial cells Moderate Uncertain
    urinary bladder urothelial cells Weak Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Moderate Uncertain
    uterus, pre-menopause cells in endometrial stroma Negative Uncertain
    uterus, pre-menopause glandular cells Moderate Uncertain
    vagina squamous epithelial cells Negative Uncertain
    vulva/anal skin epidermal cells Weak Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005634 nucleus Component
    GO:0003677 DNA binding Function
    GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding Function
    GO:0043565 sequence-specific DNA binding Function
    GO:0003700 sequence-specific DNA binding transcription factor activity Function
    GO:0007420 brain development 17353897 Process
    GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response 17566017 Process
    GO:0060706 cell differentiation involved in embryonic placenta development Process
    GO:0021895 cerebral cortex neuron differentiation Process
    GO:0001706 endoderm formation Process
    GO:0001714 endodermal cell fate specification Process
    GO:0032609 interferon-gamma production Process
    GO:0001707 mesoderm formation Process
    GO:0060809 mesodermal to mesenchymal transition involved in gastrulation Process
    GO:0021772 olfactory bulb development Process
    GO:0045597 positive regulation of cell differentiation Process
    GO:0045944 positive regulation of transcription from RNA polymerase II promoter Process
    GO:0045893 positive regulation of transcription, DNA-dependent Process
    GO:0045664 regulation of neuron differentiation Process
    GO:0019827 stem cell maintenance Process
    GO:0006351 transcription, DNA-dependent Process
    GO:0001829 trophectodermal cell differentiation Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084