Gene: DLG5

  • Entrez Gene ID

  • Symbol

    • DLG5
  • Synonyms

    • LP-DLG, P-DLG5, PDLG
  • Description

    • discs, large homolog 5 (Drosophila)
  • Type of Gene

    • protein-coding
  • Chromosome

    • 10
  • Location

    • 10q23
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    1.59
    colon
    2.35
    heart
    1.41
    hypothalamus
    1.69
    kidney
    1.45
    liver
    0.57
    lung
    0.97
    ovary
    3.01
    skeletalmuscle
    1.47
    spleen
    0.79
    testes
    3.62
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Negative Uncertain
    appendix glandular cells Negative Uncertain
    appendix lymphoid tissue Negative Uncertain
    bone marrow hematopoietic cells Negative Uncertain
    breast glandular cells Negative Uncertain
    bronchus respiratory epithelial cells Negative Uncertain
    cerebellum cells in granular layer Negative Uncertain
    cerebellum cells in molecular layer Strong Uncertain
    cerebellum Purkinje cells Negative Uncertain
    cerebral cortex glial cells Moderate Uncertain
    cerebral cortex neuronal cells Strong Uncertain
    cervix, uterine glandular cells Negative Uncertain
    cervix, uterine squamous epithelial cells Negative Uncertain
    colon glandular cells Negative Uncertain
    duodenum glandular cells Negative Uncertain
    epididymis glandular cells Weak Uncertain
    esophagus squamous epithelial cells Negative Uncertain
    fallopian tube glandular cells Negative Uncertain
    gall bladder glandular cells Negative Uncertain
    heart muscle myocytes Negative Uncertain
    hippocampus glial cells Moderate Uncertain
    hippocampus neuronal cells Strong Uncertain
    kidney cells in glomeruli Negative Uncertain
    kidney cells in tubules Negative Uncertain
    lateral ventricle glial cells Moderate Uncertain
    lateral ventricle neuronal cells Strong Uncertain
    liver bile duct cells Negative Uncertain
    liver hepatocytes Negative Uncertain
    lung macrophages Negative Uncertain
    lung pneumocytes Negative Uncertain
    lymph node germinal center cells Negative Uncertain
    lymph node non-germinal center cells Negative Uncertain
    nasopharynx respiratory epithelial cells Negative Uncertain
    oral mucosa squamous epithelial cells Negative Uncertain
    ovary ovarian stroma cells Negative Uncertain
    pancreas exocrine glandular cells Negative Uncertain
    pancreas islets of Langerhans Negative Uncertain
    parathyroid gland glandular cells Negative Uncertain
    placenta trophoblastic cells Negative Uncertain
    prostate glandular cells Negative Uncertain
    rectum glandular cells Negative Uncertain
    salivary gland glandular cells Negative Uncertain
    seminal vesicle glandular cells Negative Uncertain
    skeletal muscle myocytes Negative Uncertain
    skin epidermal cells Negative Uncertain
    small intestine glandular cells Negative Uncertain
    smooth muscle smooth muscle cells Negative Uncertain
    spleen cells in red pulp Negative Uncertain
    spleen cells in white pulp Negative Uncertain
    stomach, lower glandular cells Negative Uncertain
    stomach, upper glandular cells Negative Uncertain
    testis cells in seminiferus ducts Negative Uncertain
    testis Leydig cells Negative Uncertain
    thyroid gland glandular cells Negative Uncertain
    tonsil germinal center cells Negative Uncertain
    tonsil non-germinal center cells Negative Uncertain
    urinary bladder urothelial cells Negative Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Negative Uncertain
    uterus, pre-menopause cells in endometrial stroma Negative Uncertain
    uterus, pre-menopause glandular cells Negative Uncertain
    vagina squamous epithelial cells Negative Uncertain
    vulva/anal skin epidermal cells Weak Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0005913 cell-cell adherens junction Component
    GO:0005737 cytoplasm 9738934 Component
    GO:0005886 plasma membrane Component
    GO:0008013 beta-catenin binding 12657639 Function
    GO:0008092 cytoskeletal protein binding 12657639 Function
    GO:0030159 receptor signaling complex scaffold activity 12353226 Function
    GO:0016337 cell-cell adhesion 12353226 Process
    GO:0035556 intracellular signal transduction 12353226 Process
    GO:0008285 negative regulation of cell proliferation 9738934 Process
    GO:0042981 regulation of apoptotic process Process
    GO:0007165 signal transduction 9738934 Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084