Gene: AATK

  • Entrez Gene ID

  • Symbol

    • AATK
  • Synonyms

    • AATYK, AATYK1, LMR1, LMTK1, p35BP
  • Description

    • apoptosis-associated tyrosine kinase
  • Type of Gene

    • protein-coding
  • Chromosome

    • 17
  • Location

    • 17q25.3
  • RNA Seq 1

    Sample Expression RPKM
    adipose
    0.06
    colon
    0.27
    heart
    0.24
    hypothalamus
    6.41
    kidney
    0.08
    liver
    0.04
    lung
    0.42
    ovary
    0.06
    skeletalmuscle
    0.03
    spleen
    0.31
    testes
    0.02
  • Protein

    Tissue Cell type Staining level Reliability
    adrenal gland glandular cells Strong Uncertain
    appendix glandular cells Weak Uncertain
    appendix lymphoid tissue Negative Uncertain
    bone marrow hematopoietic cells Weak Uncertain
    breast glandular cells Negative Uncertain
    bronchus respiratory epithelial cells Negative Uncertain
    cerebellum cells in granular layer Weak Uncertain
    cerebellum cells in molecular layer Moderate Uncertain
    cerebellum Purkinje cells Weak Uncertain
    cerebral cortex glial cells Moderate Uncertain
    cerebral cortex neuronal cells Strong Uncertain
    cervix, uterine squamous epithelial cells Negative Uncertain
    colon glandular cells Moderate Uncertain
    duodenum glandular cells Moderate Uncertain
    epididymis glandular cells Moderate Uncertain
    esophagus squamous epithelial cells Weak Uncertain
    fallopian tube glandular cells Negative Uncertain
    gall bladder glandular cells Moderate Uncertain
    heart muscle myocytes Moderate Uncertain
    hippocampus glial cells Weak Uncertain
    hippocampus neuronal cells Moderate Uncertain
    kidney cells in glomeruli Negative Uncertain
    kidney cells in tubules Moderate Uncertain
    lateral ventricle glial cells Weak Uncertain
    lateral ventricle neuronal cells Moderate Uncertain
    liver hepatocytes Moderate Uncertain
    lung macrophages Moderate Uncertain
    lung pneumocytes Negative Uncertain
    lymph node germinal center cells Negative Uncertain
    lymph node non-germinal center cells Weak Uncertain
    nasopharynx respiratory epithelial cells Weak Uncertain
    oral mucosa squamous epithelial cells Negative Uncertain
    ovary follicle cells Negative Uncertain
    ovary ovarian stroma cells Negative Uncertain
    pancreas exocrine glandular cells Moderate Uncertain
    pancreas islets of Langerhans Moderate Uncertain
    parathyroid gland glandular cells Weak Uncertain
    placenta decidual cells Negative Uncertain
    placenta trophoblastic cells Weak Uncertain
    prostate glandular cells Negative Uncertain
    rectum glandular cells Moderate Uncertain
    salivary gland glandular cells Negative Uncertain
    seminal vesicle glandular cells Weak Uncertain
    skeletal muscle myocytes Moderate Uncertain
    skin epidermal cells Moderate Uncertain
    small intestine glandular cells Moderate Uncertain
    smooth muscle smooth muscle cells Negative Uncertain
    spleen cells in red pulp Weak Uncertain
    spleen cells in white pulp Negative Uncertain
    stomach, lower glandular cells Weak Uncertain
    stomach, upper glandular cells Weak Uncertain
    testis cells in seminiferus ducts Moderate Uncertain
    testis Leydig cells Moderate Uncertain
    thyroid gland glandular cells Moderate Uncertain
    tonsil germinal center cells Weak Uncertain
    tonsil non-germinal center cells Weak Uncertain
    tonsil squamous epithelial cells Weak Uncertain
    urinary bladder urothelial cells Weak Uncertain
    uterus, post-menopause cells in endometrial stroma Negative Uncertain
    uterus, post-menopause glandular cells Negative Uncertain
    uterus, pre-menopause cells in endometrial stroma Negative Uncertain
    uterus, pre-menopause glandular cells Negative Uncertain
    vagina squamous epithelial cells Weak Uncertain
    vulva/anal skin epidermal cells Negative Uncertain
  • Gene Ontology

    GO ID GO term PubMed Category
    GO:0016021 integral to membrane Component
    GO:0005739 mitochondrion 18029348 Component
    GO:0048471 perinuclear region of cytoplasm Component
    GO:0005524 ATP binding Function
    GO:0005515 protein binding 14521924 Function
    GO:0004674 protein serine/threonine kinase activity Function
    GO:0004713 protein tyrosine kinase activity Function
    GO:0006915 apoptotic process Process
    GO:0046777 protein autophosphorylation Process
  1. Krupp M et al. (2012) RNA-Seq Atlas - a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185. doi:10.1093/bioinformatics/bts084