germinal center B lymphocyte differentiation (synonym, en)
germinal center B-cell differentiation (synonym, en)
germinal center B-lymphocyte differentiation (synonym, en)
The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).